Results 141 to 150 of about 5,214 (181)
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Colloids and Surfaces B: Biointerfaces, 2001
Micellar inhibition effect of gangliosides on a degradation of drug was investigated, where ganglioside G(M1) (GM1), G(D1a) (GD1a) and G(T1b) (GTlb) whose sialic acid residue is one, two and three, respectively, were used. The base-catalyzed isomerization of prostaglandin A(2) (PGA(2)) to prostaglandin B(2) (PGB(2)) was chosen as a model experiment ...
S, Yokoyama, T, Takeda, M, Abe
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Micellar inhibition effect of gangliosides on a degradation of drug was investigated, where ganglioside G(M1) (GM1), G(D1a) (GD1a) and G(T1b) (GTlb) whose sialic acid residue is one, two and three, respectively, were used. The base-catalyzed isomerization of prostaglandin A(2) (PGA(2)) to prostaglandin B(2) (PGB(2)) was chosen as a model experiment ...
S, Yokoyama, T, Takeda, M, Abe
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Distribution of Ganglioside GM1 between Two-Component, Two-Phase Phosphatidylcholine Monolayers
Langmuir, 1998The distribution of the ganglioside GM1, at low concentrations, in phase-separated 1:1 dioleoyl phosphatidylcholine (DOPC)/dipalmitoylphosphatidylcholine (DPPC) Langmuir−Blodgett (LB) films transfe...
V. Vié +5 more
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European Journal of Biochemistry, 1980
The binding of ganglioside GM1 to bovine Serum albumin has been studied by using absorption and fluorescence properties of the protein chromophores. Differences to the ultraviolet absorption spectrum and in fluorescence quenching, as well as a marked shift of the wavelength at the fluorescences maximum provide information about the binding of this ...
Maurizio TOMASI +7 more
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The binding of ganglioside GM1 to bovine Serum albumin has been studied by using absorption and fluorescence properties of the protein chromophores. Differences to the ultraviolet absorption spectrum and in fluorescence quenching, as well as a marked shift of the wavelength at the fluorescences maximum provide information about the binding of this ...
Maurizio TOMASI +7 more
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Cholera Toxin: Interaction of Subunits with Ganglioside G M1
Science, 1974Vibrio cholerae exotoxin is an aggregate of two different noninterconvertible subunits (molecular weights about 15,000 and about 25,000). Only the smaller subunit reacts with ganglioside G M1 , a possible biological receptor.
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Interaction of multiple sclerosis serum with liposomes containing ganglioside GM1
Annals of Neurology, 1980AbstractMultiple sclerosis serum contains a factor or factors capable of releasing sequestered [14C]glucose from liposomes containing GM1, the major ganglioside present in human central nervous system myelin. Although some control sera can also release large quantities of liposomal glucose, multiple sclerosis and control sera differ in the mechanism of
B R, Mullin +3 more
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Interaction of Cholera Toxin and Ganglioside GM1
1976The exotoxin produced by Vibrio cholerae is rapidly and firmly bound to the outer membrane of mammalian cells. With simple in vitro and in vivo methods and very pure gangliosides and allied glycolipids we have demonstrated that the monosialosylganglioside GM1 is the natural receptor for the cholera toxin.
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An Immunological Model of Epilepsy: Seizures Induced by Antibodies to GM1 Ganglioside
Epilepsia, 1981Summary: Following observations that the intracerebral injection into rats of antiserum to brain gangliosides resulted in recurrent epileptiform activity and that seizure activity was not seen if antibodies were removed by absorption of the antiserum with pure GM1 ganglioside, a study was undertaken to establish characteristics of the immunological ...
S E, Karpiak +3 more
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Biological activity of preformed cholera toxin‐ganglioside GM1 complex
Journal of Neuroscience Research, 1984AbstractSynthetic and natural amphiphiles, octyl glucoside, Nonidet P40, sodium dodecyl sulfate (SDS), gangliosides GM1 and GD1a, interact with cholera toxin (CLT) and with its active region (protomer A). The formation of CLT‐amphiphile complex leads to inhibition of ADP‐ribosyltransferase activity, a characteristic of protomer A elicited after thiol ...
M L, Fiani +3 more
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Acta Neuropathologica, 2000
The post-mortem diagnosis of lysosomal storage diseases can be confounded by the unavailability of suitable material. Here we report the diagnosis of GM1-gangliosidosis in a cross-bred dog, from which only formalin-fixed brain was available, by a combination of electron microscopy and the detection of elevated levels of GM1-ganglioside within the ...
P, Whitfield +5 more
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The post-mortem diagnosis of lysosomal storage diseases can be confounded by the unavailability of suitable material. Here we report the diagnosis of GM1-gangliosidosis in a cross-bred dog, from which only formalin-fixed brain was available, by a combination of electron microscopy and the detection of elevated levels of GM1-ganglioside within the ...
P, Whitfield +5 more
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Detection of α‐Glycosidic Bonds in the Ganglioside GM1 by Stereospecific Enzymatic Degradation
European Journal of Biochemistry, 1973The monosialosyl‐N‐tetraglycosyl‐ceramide (GM1) isolated from ox brain and submitted to a stepwise degradation by specific α‐ and β‐glycosidases isolated and purified from ox spleen. By the sequential action of β‐galactosidase and β‐N‐acetylhexosaminidase, 100% of the terminal galactose and the N‐acetylgalactosamine residues were removed, while the ...
E, Werries, E, Buddecke
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