Immune Dysregulation and Self-Reactivity in Schizophrenia: Do Some Cases of Schizophrenia Have an Autoimmune Basis? [PDF]
, 2005 Schizophrenia affects 1% of the world's population, but its cause remains obscure. Numerous theories have been proposed regarding the cause of schizophrenia, ranging from developmental or neurodegenerative processes or neurotransmitter abnormalities to ...
Abramsky O +21 more
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A Cholera Toxin B-subunit Variant That Binds Ganglioside GM1 but Fails to Induce Toxicity
Journal of Biological Chemistry, 2001 Entry of cholera toxin (CT) into target epithelial cells and the induction of toxicity depend on CT binding to the lipid-based receptor ganglioside G(M1) and association with detergent-insoluble membrane microdomains, a function of the toxin's B-subunit. The B-subunits of CT and related Escherichia coli toxins exhibit a highly conserved exposed peptide
Rodighiero, Chiara +3 more
openaire +3 more sources
MARCH1 protects the lipid raft and tetraspanin web from MHCII proteotoxicity in dendritic cells [PDF]
, 2018 Dendritic cells (DCs) produce major histocompatibility complex II (MHCII) in large amounts to function as professional antigen presenting cells. Paradoxically, DCs also ubiquitinate and degrade MHCII in a constitutive manner.
Anderson +54 more
core +2 more sources
Monomer‐Micelle Transition of the Ganglioside GM1 and the Hydrolysis by Clostridium perfringens Neuraminidase [PDF]
European Journal of Biochemistry, 1979 The action of Clostridium perfringens neuraminidase on the ganglioside GM1 tritiated in the ceramide moiety was studied. The rates of hydrolysis of the GM1 ganglioside were determined from radioactivity in the neutral glycolipid product, which was separated from the substrate on DEAE‐Sephadex columns.In order to study the physical state of the ...
openaire +2 more sources
Inactivation of pathogens on food and contact surfaces using ozone as a biocidal agent [PDF]
, 2003 This study focuses on the inactivation of a range of food borne pathogens using ozone as a biocidal agent. Experiments were carried out using Campylobacter jejuni, E.
Anderson, J.G. +4 more
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Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Association of NaV1.8 with lipid rafts in DRG sensory neurons
, 2011 Voltage gated sodium channels (VGSCs) play a key role in the initiation and propagation of action potentials in neuronal cells. NaV1.8 is a Tetrodotoxin resistant VGSC expressed in nociceptors and underlies the majority of sodium currents during action
Pristera, Alessandro +1 more
core +1 more source
Tumorspecifikus ellenanyagfragmens tisztítási és tesztelési eljárásainak kidolgozása a diagnosztikus alkalmazhatóság céljából = Development of purification and test procedures of tumorspecific immunoglobulin fragments for their further diagnostic use [PDF]
, 2010 A szolid tumorokban fellelhető B sejtek kiaknázása volt a cél. A tumort infiltráló B sejtek (TIL-B) tumorspecifikus antigénkötő kapacitását nemzetközileg is elsőként igazoltuk. Az eljárás diagnosztikus célú tumorfelismerő "jelölő molekulákat" eredményez.
Kotlán, Beatrix +3 more
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