Results 51 to 60 of about 11,803,234 (178)

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, Volume 293, Issue 11, Page 3187-3210, June 2026.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

Gangglioside G(M1) 이 함유된 liposome 의 구조와 안정도에 관한 연구

, 1989
학위논문(석사) - 한국과학기술원 : 화학공학과, 1989.2, [ [iv], 134 p. ]The thermotropic behavior and vesicle fusion of aqueous dispersions of L-α-dipalmitoylphosphatidylcholine (DPPC)-Ganglioside G(M1) mixtures have been determined by High sensitivity differential ...
Choung, Aun-Kyo, 정언교
core   +1 more source

Metabolic processing of gangliosides by normal and Salla human fibroblasts in culture - A study performed by administering radioactive G(M3) ganglioside

, 1996
Cultured fibroblasts from normal subjects and from subjects affected by Salla disease, characterized by the lack or misfunction of the membrane carrier responsible for the egress of sialic acid from lysosomes, were fed with ganglioside G(M3) labeled at ...
V. Chigorno, G. Tettamanti, S. Sonnino
core   +1 more source

SYK Signalling in NLRP3 Inflammasome‐Mediated Response of Murine Microglia Activated by Immune Complexes Formed of Viral Proteins and Specific IgG

European Journal of Immunology, Volume 56, Issue 5, May 2026.
IC‐mediated inflammatory response—the NLRP3 inflammasome activation, cytokine secretion, and antigen presentation depend on SYK signalling pathways in primary murine microglia. ABSTRACT Viral infections might trigger systemic inflammatory responses characterised by inflammasome activation and cytokine release, driven by immune complex (IC) formation ...
Kristina Mašalaitė, Milda Norkienė, Aurelija Žvirblienė, Asta Lučiūnaitė   +3 more
wiley   +1 more source

Ganglioside Formation

, 2021
Dr.
Andrew G. Lee, MD; Shangyi Fu
core  

Quartz crystal microbalance investigation of the interaction of bacterial toxins with ganglioside containing solid supported membranes

, 1997
The binding of cholera toxin, tetanus toxin and pertussis toxin to ganglioside containing solid supported membranes has been investigated by quartz crystal microbalance measurements.
Janshoff, Andreas, Schmidt, Marcus Alexander, Steinem, Claudia, Sieber, Manfred, Galla, Hans-Joachim, Bayâ, A. el   +5 more
core   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Synthesis of a Fluorescent Ganglioside G_M1 Derivative and Screening of a Synthetic Peptide Library for G_M1 Binding Sequence Motifs

, 2016
A ganglioside GM1 probe bearing a dark-red fluorescent dye at the sphingosine moiety of the molecule was prepared by a convenient one-pot synthesis.
Andreas Frey (112576), Steffen Bade (2176082), Hans H. Gorris (1413865), Timothy R. Hirst (2499712), Niels Röckendorf (112567)   +4 more
core   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Ganglioside/glycosphingolipid turnover : new concepts

, 2003
In this review focus is given to the metabolic turnover of gangliosides/glycosphingolipids. The metabolism and accompanying intracellular trafficking of gangliosides/glycosphingolipids is illustrated with particular attention to the following events: (a)
G. Tettamanti
core   +1 more source