Results 181 to 190 of about 396,098 (353)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis. [PDF]

Sci Rep, 2022
Xu G, Gong Y, Lu F, Wang B, Yang Z, Chen L, Min J, Cheng C, Jiang T.   +8 more
europepmc   +1 more source

G-Protein–Coupled Receptor Kinase Activity in Hypertension [PDF]

, 2000
Robert Gros, Jozef Chorazyczewski, Murray D. Meek, Jeffrey Benovic, Stephen S. G. Ferguson, Ross D. Feldman   +5 more
openalex   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

Kinase Activity Is Not Required for G Protein-Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development.

J Am Soc Nephrol, 2023
Gerhards J, Maerz LD, Matthees ESF, Donow C, Moepps B, Premont RT, Burkhalter MD, Hoffmann C, Philipp M.   +8 more
europepmc   +1 more source

Mutational Analysis of Gβγ and Phospholipid Interaction with G Protein-coupled Receptor Kinase 2 [PDF]

, 2000
Christopher V. Carman, Larry S. Barak, Chongguang Chen, Lee‐Yuan Liu‐Chen, James J. Onorato, Scott P. Kennedy, Marc G. Caron, Jeffrey Benovic   +7 more
openalex   +1 more source

Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development [PDF]

, 1999
The ErbB2 tyrosine kinase functions as coreceptor for the neuregulin receptors ErbB3 and ErbB4 and can participate in signaling of EGF receptor (ErbB1), interleukin receptor gp130, and G-protein coupled receptors.
Abou-Rebyeh, Faikah, Birchmeier, Carmen, Britsch, Stefan, Caroni, Pico, Harvey, Richard, Riethmacher, Dieter, Sonnenberg-Riethmacher, Eva, Woldeyesus, Masresha T., Xu, Lan   +8 more
core  

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation. [PDF]

Clin Sci (Lond), 2022
Zhang F, Lei L, Huang J, Wang W, Su Q, Yan H, Chen C, Zheng S, Ren H, Li Z, Jose PA, Hu Y, Si L, Zeng C, Yang J.   +14 more
europepmc   +1 more source

Dual Requirement for Rho and Protein Kinase C in Direct Activation of Phospholipase D1 Through G Protein-coupled Receptor Signaling [PDF]

, 2000
Guangwei Du, Yelena M. Altshuller, Yong Kim, Jung Min Han, Sung Ho Ryu, Andrew J. Morris, Michael A. Frohman   +6 more
openalex   +1 more source