Results 171 to 180 of about 536,609 (348)

A novel octopamine receptor with preferential expression in Drosophila mushroom bodies [PDF]

, 1998
Octopamine is a neuromodulator that mediates diverse physiological processes in invertebrates. In some insects, such as honeybees and fruit flies, octopamine has been shown to be a major stimulator of adenylyl cyclase and to function in associative ...
Han, K-A, Millar, NS
core  

G-Protein–Coupled Receptor Kinase 2 as a Potential Modulator of the Hallmarks of Cancer

Molecular Pharmacology, 2017
Laura Nogués, Clara Reglero, Verónica Rivas, María Neves, P. Penela, Federico Mayor   +5 more
semanticscholar   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Kinase Activity Is Not Required for G Protein-Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development. [PDF]

J Am Soc Nephrol, 2023
Gerhards J, Maerz LD, Matthees ESF, Donow C, Moepps B, Premont RT, Burkhalter MD, Hoffmann C, Philipp M.   +8 more
europepmc   +1 more source

G protein-coupled receptor kinase 4 gene variants in human essential hypertension

Proceedings of the National Academy of Sciences of the United States of America, 2002
R. Felder, H. Sanada, Jing Xu, P. Yu, Z. Wang, H. Watanabe, L. Asico, Wei Wang, Shaopeng Zheng, I. Yamaguchi, Scott M. Williams, J. Gainer, N. Brown, D. Hazen‐Martin, Lee-Jun C. Wong, J. Robillard, R. Carey, G. Eisner, P. Jose   +18 more
semanticscholar   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

G Protein-Coupled Receptor Kinase 4 Is a Novel Prognostic Factor in Hepatocellular Carcinoma. [PDF]

Dis Markers, 2022
Luo Y, Wang Z, Xiao S, Li R, Jiang X.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2. [PDF]

Front Pharmacol, 2023
Burström V, Ågren R, Betari N, Valle-León M, Garro-Martínez E, Ciruela F, Sahlholm K.   +6 more
europepmc   +1 more source

The complex G protein‐coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets

British Journal of Pharmacology, 2010
P. Penela, C. Murga, C. Ribas, V. Lafarga, Federico Mayor, Jr.   +4 more
semanticscholar   +1 more source