Results 221 to 230 of about 426,123 (306)

G-protein coupled receptor kinase-2 regulates the migration of chronic lymphocytic leukaemia cells to sphingosine-1 phosphate in vitro and their trafficking in vivo. [PDF]

Sci Rep
Cassarino MC, Colado A, Martinez VS, Martines C, Bonato A, Bertini M, Pavlovksy M, Custidiano R, Bezares FR, Morande PE, Vermeulen M, Gamberale R, Giordano M, Efremov DG, Borge M.   +14 more
europepmc   +1 more source

The structure of the skeletal and nonskeletal muscle calcium channel [PDF]

, 1989
Biel, Martin, Felbel, J., Flockerzi, Veit, Gehring, U., Hofmann, Franz, Nastainczyk, E., Regulla, S., Ruth, Peter, Schneider, T.   +8 more
core   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Quantitative proteomics assay reveals G protein-coupled receptor kinase 4-induced HepG2 cell growth inhibition. [PDF]

Heliyon
Luo Y, Yang J, Wang Y.
europepmc   +1 more source

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

Advanced Healthcare Materials, EarlyView.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin, Sean P. Doidge, Eiman Aleem, Suela Kellici, Steven Dunn, Claire Atkinson, Philip D. Howes   +6 more
wiley   +1 more source

Nonenzymatic Rapid Control of GIRK Channel Function by a G Protein-Coupled Receptor Kinase [PDF]

, 2010
Adi Raveh, Ayelet Cooper, Liora Guy-David, Eitan Reuveny   +3 more
openalex   +1 more source

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

Advanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim, Sung Sik Hur, Jae Hong Park, Myung Jin Ban, Jin‐Young Kim, Joo Hyun Kim, Ji Hyae Choo, Hae‐Won Kim, Ju Hun Lee, Man Ryul Lee, Yongsung Hwang   +10 more
wiley   +1 more source

Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexes. [PDF]

Eur J Med Chem
Chen Y, Sonawane A, Manda R, Gadi RK, Tesmer JJG, Ghosh AK.   +5 more
europepmc   +1 more source

Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6

, 2009
Kirsten M. Raehal, Cullen L. Schmid, Ivan O. Medvedev, Raul R. Gainetdinov, Richard T. Premont, Laura Bohn   +5 more
openalex   +1 more source

Heterotrimeric G protein β ₁ γ ₂ subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane [PDF]

, 2011
Andrew P. Boughton, Pei Yang, Valerie M. Tesmer, Bei Ding, J.J.G. Tesmer, Zhan Chen   +5 more
openalex   +1 more source