Results 211 to 220 of about 536,609 (348)

G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation. [PDF]

Clin Sci (Lond), 2022
Zhang F, Lei L, Huang J, Wang W, Su Q, Yan H, Chen C, Zheng S, Ren H, Li Z, Jose PA, Hu Y, Si L, Zeng C, Yang J.   +14 more
europepmc   +1 more source

G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton.

Molecular Biology of the Cell, 2005
S. H. Cant, J. Pitcher
semanticscholar   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

The role of G protein-coupled receptor kinase 4 in cardiomyocyte injury after myocardial infarction. [PDF]

Eur Heart J, 2021
Li L, Fu W, Gong X, Chen Z, Tang L, Yang D, Liao Q, Xia X, Wu H, Liu C, Tian M, Zeng A, Zhou L, Jose PA, Chen K, Wang WE, Zeng C.   +16 more
europepmc   +1 more source

Mdm2 is involved in the ubiquitination and degradation of G‐protein‐coupled receptor kinase 2

EMBO Journal, 2006
Alicia Salcedo, F. Mayor, P. Penela
semanticscholar   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

G-Protein-Coupled Receptor Kinase 2 Limits CCL21-Induced T Cell Migration via Phospholipase Cγ1. [PDF]

Receptors (Basel)
Sanchez A, Winebrenner CT, Garcia N, Kaiser B, Kilgore L, Cardona CI, Bassuk DW, Miller ME, Bill CA, Shannon LA, Wagener BM, Wagler A, Llano M, Bill CA, Vines CM.   +14 more
europepmc   +1 more source

The Hypertension Related Gene G-Protein Coupled Receptor Kinase 4 Contributes to Breast Cancer Proliferation. [PDF]

Breast Cancer (Auckl), 2021
Yue W, Tran HT, Wang JP, Schiermeyer K, Gildea JJ, Xu P, Felder RA.   +6 more
europepmc   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Potent, Selective, and Drug-Like G Protein-Coupled Receptor Kinase 5 and 6 Inhibitors: Design, Synthesis, and X-Ray Structural Studies. [PDF]

ChemMedChem
Ghosh AK, Gadi RK, Chen Y, Gamage SP, McCauley KP, Tesmer JJG.   +5 more
europepmc   +1 more source