Results 251 to 260 of about 776,363 (406)

Multiple G Protein-Coupled Receptors Initiate Protein Kinase C Redistribution of GABA Transporters in Hippocampal Neurons

, 1999
Matthew L. Beckman, E. M. Bernstein, Michael W. Quick   +2 more
openalex   +1 more source

A Truncated Form of RGS3 Negatively Regulates G Protein-coupled Receptor Stimulation of Adenylyl Cyclase and Phosphoinositide Phospholipase C [PDF]

, 1997
Tapan K. Chatterjee, Alex Eapen, Rory A. Fisher   +2 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Mechanisms of Peptide Agonist Dissociation and Deactivation of Adhesion G-Protein-Coupled Receptors. [PDF]

Biochemistry
Joshi K, Miao Y.
europepmc   +1 more source

Acute loss of Cell–Cell Communication Caused by G Protein–coupled Receptors: A Critical Role for c-Src [PDF]

, 1998
Friso R. Postma, Trudi Hengeveld, Jacqueline Alblas, Ben N. G. Giepmans, Gerben Zondag, Kees Jalink, Wouter H. Moolenaar   +6 more
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Astrocytic G Protein-Coupled Receptors in Drug Addiction. [PDF]

Engineering (Beijing)
Zinsmaier AK, Nestler EJ, Dong Y.
europepmc   +1 more source

Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. [PDF]

, 1996
Martin Oppermann, Marı́a A. Diversé-Pierluissi, Mark H. Drazner, Shanny L. Dyer, Neil J. Freedman, Karsten Peppel, Robert J. Lefkowitz   +6 more
openalex   +1 more source

G-Protein-Coupled Receptors in Astrocyte–Neuron Communication

Neuroscience, 2020
P. Kofuji, A. Araque
semanticscholar   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source