Mutational Analysis of the Relative Orientation of Transmembrane Helices I and VII in G Protein-coupled Receptors [PDF]
Jie Liu +3 more
openalex +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
G-protein coupled receptors synergy in bone health: new avenues for osteoporosis detection and <i>in vitro</i> modeling. [PDF]
Sopova JV +7 more
europepmc +1 more source
Erratum: Biased ligands at G protein-coupled receptors: promise and progress [PDF]
Jonathan D. Violin +3 more
openalex +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Structural diversity of G protein-coupled receptors and significance for drug discovery
M. Lagerström, H. Schiöth
semanticscholar +2 more sources
Autoimmunity in MASLD: Focus on autoantibodies, anti-apolipoprotein A1 IgG and G protein-coupled receptors. [PDF]
Pagano S +3 more
europepmc +1 more source
Insights into G-Protein Coupled Receptors Activation from All-Atom Molecular Dynamics Simulations [PDF]
Stefano Vanni +3 more
openalex +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source

