Results 191 to 200 of about 5,882,179 (311)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Effect of Ropivacain and Bupivacain on Calcium-Related and G-Protein Coupled Processes in PMNs: A Human In-Vitro Study. [PDF]

Health Sci Rep
Kraus RF, Galla T, Gruber M, Wittmann S.
europepmc   +1 more source

Structure-function analysis of plant G-protein regulatory mechanisms identifies key Gα-RGS protein interactions [PDF]

María Daniela Torres-Rodríguez, Soon Goo Lee, Swarup Roy Choudhury, Rabindranath Paul, Balaji Selvam, Diwakar Shukla, Joseph M. Jez, Sona Pandey   +7 more
openalex   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

State-Specific Peptide Design Targeting G Protein-Coupled Receptors. [PDF]

J Chem Inf Model
Xue Y, Wang H, Li J, Hu J, Chen Z, Zheng Z, Liu L, Zhu K, He J, Gong H, Li X, Zhang X, Fang X.   +12 more
europepmc   +1 more source

Inside‐Out IP ₃ ‐Mediated G Protein‐Coupled Receptor Activation Drives Intercellular Ca ²⁺ Signaling in the Vascular Endothelium [PDF]

Charlotte Buckley, Xun Zhang, Matthew D. Lee, Calum Wilson, John G. McCarron   +4 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Rapid purification of brain protein complexes containing active and inactive forms of the G protein Gαo. [PDF]

PLoS One
Yadav S, Veliventi SS, Meena S, Koelle MR, Kumar S.   +4 more
europepmc   +1 more source

Analysis of stimulation-G protein subunit coupling by using active insulin-like growth factor II receptor peptide.

, 1991
Toru Okamoto, Ikuo Nishimoto
openalex   +2 more sources