Results 191 to 200 of about 21,426,917 (362)

G-proteins in skeletal muscle. Evidence for a 40 kDa pertussis-toxin substrate in purified transverse tubules [PDF]

, 1988
Madeleine Toutant, Jacques Barhanin, Joël Bockaert, B. Rouot   +3 more
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Human cytomegalovirus-encoded G protein-coupled receptor (GPCR) UL78 regulates viral reactivation. [PDF]

J Virol
Osanyinlusi SA, Baruah V, Groves IJ, Kulp KH, Krishna BA, O'Connor CM.   +5 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Identification and localization of adhesion G protein-coupled receptor expression in the murine kidney. [PDF]

Am J Physiol Renal Physiol
Steichen H, Xue J, Zaidman NA.
europepmc   +1 more source

High-mobility group protein HMG-I localizes to G/Q- and C-bands of human and mouse chromosomes. [PDF]

, 1989
Jane Disney, Kenneth R. Johnson, Nancy S. Magnuson, Steven R. Sylvester, Raymond Reeves   +4 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Structural insights into ligand recognition and G protein preferences across histamine receptors. [PDF]

Commun Biol
Matsuzaki Y, Sano FK, Oshima HS, Akasaka H, Kobayashi K, Tanaka T, Itoh Y, Shihoya W, Kise Y, Kusakizako T, Inoue A, Nureki O.   +11 more
europepmc   +1 more source

Isolation and characterization of a 14-kDa albumin-binding fragment of streptococcal protein G. [PDF]

, 1988
Ulf Sjöbring, Cecilia Falkenberg, Erik Nielsen, Bo Åkerström, Lars Björck   +4 more
openalex   +1 more source

Serial Femtosecond Crystallography of G Protein-Coupled Receptors.

Annual Review of Biophysics, 2018
B. Stauch, V. Cherezov
semanticscholar   +1 more source