d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada+3 more
wiley +1 more source
Stimulatory and inhibitory G-protein signaling relays drive cAMP accumulation for timely metamorphosis in the chordate <i>Ciona</i>. [PDF]
Hozumi A+9 more
europepmc +1 more source
PoDCall: a robust tool for automated droplet classification in DNA‐methylation droplet digital PCR
Molecular Oncology, EarlyView.
Hans Petter Brodal+3 more
wiley +1 more source
Earthing effects on mitochondrial function: ATP production and ROS generation
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source
When G Protein-Coupled Receptor Signaling Meets the Primary Cilium: Implications for Sonic Hedgehog Signaling. [PDF]
Kim SE.
europepmc +1 more source
Why Are Cytomegalovirus-Encoded G-Protein-Coupled Receptors Essential for Infection but Only Variably Conserved? [PDF]
Fares S, Krishna BA.
europepmc +1 more source
Covalent functionalization of G protein-coupled receptors by small molecular probes. [PDF]
Beerkens BLH+3 more
europepmc +1 more source
Thermosensory Roles of G Protein-Coupled Receptors and Other Cellular Factors in Animals. [PDF]
Ohnishi K, Sokabe T.
europepmc +1 more source
The cardioprotective role of the G protein-coupled receptor FFAR4 in atherosclerosis is independent of macrophage foam cell regulation. [PDF]
Stuttgen GM+4 more
europepmc +1 more source