Results 41 to 50 of about 21,743,586 (235)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
, 1992 "A/B G. W. Ireland H.M.A.S. Platypus P.A. 1827. 1941 - 1943".Index to the location of names on the quilt ; A6Able Seamn G. W. Ireland. His Majesty's Australian Ship Platypus. P.A. 1827.
Ireland, G. W.
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Hearing Loss due to Infiltration of the Tympanic Membrane by Chronic Lymphocytic Leukemia
Case Reports in Hematology, 2012 Central nervous system (CNS) involvement by chronic lymphocytic leukemia (CLL) can present with dramatic neurologic findings or can be quite subtle, discovered only at the time of autopsy.
Jonathon B. Cohen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Modele doboru metod w rozwiązywaniu problemów zarządzania w ujęciu G. Nadlera
Zeszyty Naukowe Uniwersytetu Ekonomicznego w Krakowie, 2016 Zwiększanie efektywności organizacji jako kategorii mieszczącej się w naukach o zarządzaniu stanowi jedno z ważniejszych wyzwań zarówno praktyków, jak i teoretyków tej dyscypliny naukowej. Odpowiedni dobór metod w rozwiązywaniu problemów zarządzania jest
Marek Szarucki
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Administrator's Sale, W. G. Harris land, Perryville, Perry County, Ark., 1909.
, 2013 Notice of Administrator's sale given by W. G. Harris, Administrator of the estate of W. G. Harris, deceased, to be held on Tuesday, August 10, 1909, at the Perry County courthouse, Perryville, Arkansas, by order of the probate court of the Western ...
Duncan, W. M., -1909
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source