The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Interazione ludica, tra dinamiche screen-based e product-based
Il volume tratta di esperienze di progettazione e prototipazione sulla tematica dell’interaction design, trattata nell’ambito del corso di laboratorio di Advanced Product Design del Corso di Laurea Magistrale in Design dell’Università degli Studi di ...
Goretti G
core
In silico, in vitro, and in vivo evaluation of the antiviral potential of glycyrrhizic acid and chitosan nanoparticles against foot and mouth disease virus. [PDF]
Eweis ARF +5 more
europepmc +1 more source
Review on Genetic, Environment and Their Interaction (G x E) for Stability of Coffee Quality
openaire +2 more sources
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Cryo-EM structure of the interleukin-31 receptor complex defines non-canonical interactions that confer receptor specificity. [PDF]
Feng Y, Qian G, Wei Z, Dong X.
europepmc +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Electron-withdrawing group effects on the structural, electronic, reactivity, and binding characteristics of triazolopyrimidine herbicides: a comparative study of diclosulam, cloransulam-methyl, and cloransulam. [PDF]
Potla KM +6 more
europepmc +1 more source
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
AlloPool is a deep learning framework that infers protein allostery from molecular dynamics simulations. [PDF]
Marfoglia M +4 more
europepmc +1 more source

