Results 171 to 180 of about 46,574,544 (297)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Dipole-dipole interaction facilitates anion-rich solvation structures in polymer electrolytes for solid-state lithium metal batteries. [PDF]

Sci Adv
Shuang ZY, Zhao CZ, Huang XY, Gao YC, Xu P, Fu F, Oh Y, Kong WJ, Huang WZ, Li YF, Wang ZY, Wang ZX, Chen X, Ling C, Huang JQ, Zhang Q.   +15 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

MATEMATICA(MENTE) POSSIBILE. I SERVIZI EROGATI AGLI STUDNETI CON DSA PRESSO L'UNIVERSITA' DEGLI STUDI DI MODENA E REGGIO EMILIA

, 2013
Indagini recenti indicano come oggi in Italia sia crescente il numero degli studenti di ogni ordine e grado scolastico che incontrano problemi nell'apprendimento del sistema dei numeri, manifestando difficoltà relative a: riconoscimento e denominazione ...
GUZZO F, GENOVESE E, GUARALDI G
core  

GNL3 SUMOylation is essential for DNA double-strand break repair by homologous recombination. [PDF]

Nat Commun
Yang Y, Li Y, Dai RS, Chen C, Zientek K, Reddy AP, Xia Z, Sears RC, Sun XX, Dai MS.   +9 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Multi-model assessment of yield stability in lentil across multi-environments. [PDF]

PLoS One
Asghar MJ, Ghaffar M, Shahid M, Akhtar KP, Hameed A, Tabasum A, Rabbani G, Javed U, Shahbaz MU, Kamran M, Ehtisham-Ul-Haq M.   +10 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

G. SERRELI, L'insediamento nel territorio di Muravera e nelle curadorìas di Colostrai, Sarrabus e Quirra fra il Medioevo e la prima Età Moderna, in Torri, Territorio e Mare a cura di M.G. Mele e G. Serreli, Consiglio Nazionale delle Ricerche - Istituto di Storia dell'Europa Mediterranea, Cagliari 2008, pp. 47-71

, 2008
Analisi dell'insediamento medievale nelle curadorìas di Sarrabus, Colostrai e Quirra fra il Regno di Càlari (X-1258), la dominazione pisana (1258-1323) e il Regno di 'Sardegna e Corsica' (1324 - XV secolo), attraverso le fonti, i dati archeologici e la
GIOVANNI, SERRELI
core  

Enhancing the preservation of chicken breast using a curdlan/BSA gel interacted with citrus flavonoids: Interaction mode and dual-component protection. [PDF]

Food Chem X
Salah M, Hassan MF, Khalifa I, Mansour M, Hu B, Liu Y, Zhu Q.   +6 more
europepmc   +1 more source