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B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
Nature, 2021Yuki Sugiura, Kenji Chamoto, Rei Nakano
exaly
1987
γ-Aminobutyric acid is the major inhibitory neurotransmitter in the central nervous system and is widely utilized in virtually all anatomic regions of the brain and spinal cord [1,2]. In recent years, pharmacological evidence at all levels (organismal, tissue, cellular, and molecular) have implicated GABA in a variety of human clinical problems and ...
openaire +2 more sources
γ-Aminobutyric acid is the major inhibitory neurotransmitter in the central nervous system and is widely utilized in virtually all anatomic regions of the brain and spinal cord [1,2]. In recent years, pharmacological evidence at all levels (organismal, tissue, cellular, and molecular) have implicated GABA in a variety of human clinical problems and ...
openaire +2 more sources
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
Nature Cell Biology, 2022De Huang, Yan Wang, J Will Thompson
exaly
GABA tone regulation and its cognitive functions in the brain
Nature Reviews Neuroscience, 2023Wuhyun Koh, , Eunji Cheong
exaly