Results 1 to 10 of about 179,337 (237)
Scientific Reports, 2022 Understanding the phenotypic and functional diversity of cerebral cortical GABAergic neurons requires a comprehensive analysis of key transcriptional signatures and neuronal subtype identity.
Shiyou Wang +8 more
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Nicotine Addiction: Neurobiology and Mechanism
Journal of Pharmacopuncture, 2020 Nicotine, primary component of tobaco produces craving and withdrawal effect both in humans and animals. Nicotine shows a close resemblance to other addictive drugs in molecular, neuroanatomical and pharmacological, particularly the drugs which enhances ...
Raj Kumar Tiwari +3 more
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The Expanding Therapeutic Potential of Neuronal KCC2
Cells, 2020 Dysfunctions in GABAergic inhibitory neural transmission occur in neuronal injuries and neurological disorders. The potassium−chloride cotransporter 2 (KCC2, SLC12A5) is a key modulator of inhibitory GABAergic inputs in healthy adult neurons, as ...
Bor Luen Tang
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Distinct roles for inhibition in spatial and temporal tuning of local edge detectors in the rabbit retina. [PDF]
, 2014 This paper examines the role of inhibition in generating the receptive-field properties of local edge detector (LED) ganglion cells in the rabbit retina. We confirm that the feed-forward inhibition is largely glycinergic but, contrary to a recent report,
Buldyrev, Ilya +5 more
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Divergent modulation of nociception by glutamatergic and GABAergic neuronal subpopulations in the periaqueductal gray [PDF]
, 2017 The ventrolateral periaqueductal gray (vlPAG) constitutes a major descending pain modulatory system and is a crucial site for opioid-induced analgesia. A number of previous studies have demonstrated that glutamate and GABA play critical opposing roles in
Bruchas, Michael R +7 more
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Frontiers in Cellular Neuroscience, 2020 The current study investigates the neurotrophic effects of Clostridium botulinum C3 transferase (C3bot) on highly purified, glia-free, GABAergic, and glutamatergic neurons.
Andrej Adolf +6 more
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Modulation of the GABAergic pathway for the treatment of fragile X syndrome. [PDF]
, 2014 Fragile X syndrome (FXS) is the most common genetic cause of intellectual disability and the most common single-gene cause of autism. It is caused by mutations on the fragile X mental retardation gene (FMR1) and lack of fragile X mental retardation ...
Hagerman, Randi J +2 more
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Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia. [PDF]
PLoS Biology, 2011 Although retinoic acid (RA) has been implicated as an extrinsic signal regulating forebrain neurogenesis, the processes regulated by RA signaling remain unclear.
Christina Chatzi +2 more
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Frontiers in Pharmacology, 2023 Background: The histaminergic neurons in the hypothalamic tuberomammillary nucleus (TMN) have been suggested to play a vital role in maintaining a rising state.
Jing Liu +31 more
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Metamodulation of a spinal locomotor network by nitric oxide [PDF]
, 2004 Flexibility in the output of spinal networks can be accomplished by the actions of neuromodulators; however, little is known about how the process of neuromodulation itself may be modulated.
McLean, DL, Sillar, Keith Thomas
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