Role for TGF-beta superfamily signaling in telencephalic GABAergic neuron development. [PDF]
Signaling mechanisms mediated by the Transforming Growth Factor-beta (TGF-beta) superfamily regulate a variety of developmental processes. Here we show that components of both bone morphogenetic protein/growth differentiation factor and TGF-beta/activin ...
Lee, Amie Y +4 more
core
Dysfunctional GABAergic inhibition in the prefrontal cortex leading to "psychotic" hyperactivation [PDF]
Shoji Tanaka
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GABAergic projections to the oculomotor nucleus in the goldfish (Carassius auratus)
The mammalian oculomotor nucleus receives a strong -aminobutyric acid (GABA)ergic synaptic input, whereas such projections have rarely been reported in fish.
M. Angeles eLuque +4 more
doaj +1 more source
Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment. [PDF]
Ras/MAPK pathway signaling is a major participant in neurodevelopment, and evidence suggests that BRAF, a key Ras signal mediator, influences human behavior.
Camacho, FM +10 more
core
Maturation of the GABAergic Transmission in Normal and Pathologic Motoneurons [PDF]
Anne‐Emilie Allain +6 more
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The double role of GABAergic system in systemic tumors: an updated review
The GABAergic system is the main inhibitory nervous system. In addition, GABA has been reported to affect tumor growth and its expression differs between tumor tissue and normal tissue.
Xueyang Yang +5 more
doaj +1 more source
Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Benigno, Arcangelo +6 more
core +1 more source
Cholinergic and GABAergic pathways in fly motion vision [PDF]
Tilmann M. Brotz +2 more
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Understanding GABAergic synapse diversity and its implications for GABAergic pharmacotherapy
Despite the substantial contribution of disruptions in GABAergic inhibitory neurotransmission to the etiology of psychiatric, neurodevelopmental, and neurodegenerative disorders, surprisingly few drugs targeting the GABAergic system are currently available, partly due to insufficient understanding of circuit-specific GABAergic synapse biology.
openaire +3 more sources

