Results 11 to 20 of about 179,337 (237)

Hippocampal GABAergic Inhibitory Interneurons [PDF]

Physiological Reviews, 2017
In the hippocampus GABAergic local circuit inhibitory interneurons represent only ~10–15% of the total neuronal population; however, their remarkable anatomical and physiological diversity allows them to regulate virtually all aspects of cellular and circuit function. Here we provide an overview of the current state of the field of interneuron research,
Pelkey, Kenneth A., Chittajallu, Ramesh, Craig, Michael T., Tricoire, Ludovic, Wester, Jason C., McBain, Chris J.   +5 more
openaire   +4 more sources

GABAergic Synchronization in Epilepsy [PDF]

Cold Spring Harbor Perspectives in Medicine, 2016
γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the cerebral cortex. GABAergic inhibition enables synchronization of activity in cortical networks, and contributes to generation of variety of brain activity patterns. In relation to epilepsy, GABAergic inhibition has been traditionally viewed as the main mechanism counterbalancing ...
openaire   +4 more sources

The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia [PDF]

, 2019
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
A.M. Lavoie, AR Woodruff, C Börgers, C-G Hahn, CA Brenner, Chi-Ming A. Chen, CL Beasley, D Vierling-Claassen, D Vierling-Claassen, David A. Lewis, David W. Volk, E Salinas, G Gonzalez-Burgos, GA Light, GP Krishnan, Hanna Thuné, Henry Markram, I Wonodi, J. Szabadics, Joshua T. Kantrowitz, JS Kwon, KM Spencer, KM Spencer, KM Spencer, L KRISTIANSEN, LS Overstreet, M Bartos, M Carlén, Monica Beneyto, Monika P. Jadi, MW Howard, N Hajos, Nadezhda V. Povysheva, P Fries, P Steullet, P Teale, Pascal Fries, R Tsuchimoto, Robin Tremblay, RY Cho, S Keros, T Hashimoto, T Mäki-Marttunen, T-U Woo, Tuomo Mäki-Marttunen, Y Kawaguchi   +45 more
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Distribution of GABAergic cells in the inferior colliculus that project to the thalamus

Frontiers in Neuroanatomy, 2014
A GABAergic component has been identified in the projection from the inferior colliculus (IC) to the medial geniculate body (MG) in cats and rats. We sought to determine if this GABAergic pathway exists in guinea pig, a species widely used in auditory ...
Jeffrey G Mellott, Nichole L Foster, Nichole L Foster, Kyle T Nakamoto, Susan D Motts, Brett R Schofield, Brett R Schofield   +6 more
doaj   +1 more source

Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit [PDF]

, 2009
The striatum, the principal input structure of the basal ganglia, is crucial to both motor control and learning. It receives convergent input from all over the neocortex, hippocampal formation, amygdala and thalamus, and is the primary recipient of ...
Alexander, Bar-Gad, Bauswein, Beiser, Belluardo, Berke, Berke, Bevan, Blackwell, Bolam, Bracci, Bracci, Brown, Burke, Buzsaki, Carrillo-Reid, Centonze, Cho, Czubayko, Dawson, Djurfeldt, Ferro, Frank, Fukai, Galan, Galarreta, Galvan, Gerfen, Glynn, Gonon, Gorelova, Groenewegen, Gurney, Humphries, Humphries, Humphries, Hurd, Ingham, Izhikevich, Izhikevich, Jaeger, Jahr, Kawaguchi, Kawaguchi, Kevin Gurney, Kirik, Kita, Koos, Koos, Kubota, Kwok, Lago-Fernandez, Mallet, Mark D. Humphries, Markram, McGeorge, Miller, Moyer, Newman, Newman, Nisenbaum, Nishikawa, Oorschot, O’Donnell, Pennartz, Plenz, Redgrave, Ric Wood, Richtand, Sandstrom, Schultz, Schwarting, Smith, Sullivan, Surmeier, Tang, Tateno, Taverna, Tepper, Traub, Tseng, Tunstall, Turner, Venton, Wang, Watts, Whishaw, Wickens, Wickens, Wilson, Yin, Zheng, Zhou   +92 more
core   +1 more source

Inhibitory or excitatory? Optogenetic interrogation of the functional roles of GABAergic interneurons in epileptogenesis

Journal of Biomedical Science, 2017
Alteration in the excitatory/inhibitory neuronal balance is believed to be the underlying mechanism of epileptogenesis. Based on this theory, GABAergic interneurons are regarded as the primary inhibitory neurons, whose failure of action permits ...
Hui Ye, Stephanie Kaszuba
doaj   +1 more source

The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors

Biology Open, 2013
Summary Midbrain- and hindbrain-derived GABAergic interneurons are critical for regulation of sleep, respiratory, sensory-motor and motivational processes, and they are implicated in human neurological disorders.
Kaia Achim, Paula Peltopuro, Laura Lahti, Hui-Hsin Tsai, Alyssa Zachariah, Mia Åstrand, Marjo Salminen, David Rowitch, Juha Partanen   +8 more
doaj   +1 more source

The Effect of GABAergic Cells Transplantation on Allodynia and Hyperalgesia in Neuropathic Animals: A Systematic Review With Meta-Analysis

Frontiers in Neurology, 2022
The role of GABAergic cell transplantation in improving neuropathic pain is controversial. We comprehensively searched the relevant literature to identify animal studies of GABAergic cell transplantation that recorded pain behaviors as an outcome ...
Zhen-Rong Zhang, Zhen-Rong Zhang, Yao Wu, Yao Wu, Wen-Jing Wang, Wen-Jing Wang, Fang-Yong Wang, Fang-Yong Wang   +7 more
doaj   +1 more source

Thyroid hormone-dependent development of early cortical networks: Temporal specificity and the contribution of trkB and mTOR pathways

Frontiers in Cellular Neuroscience, 2013
Early in neocortical network development, triiodothyronine (T3) promotes GABAergic neurons’ population increase, their somatic growth and the formation of GABAergic synapses. In the presence of T3, GABAergic interneurons form longer axons and conspicuous
Sören eWesterholz, Ana D. de Lima, Thomas eVoigt, Thomas eVoigt   +3 more
doaj   +1 more source

The early excitatory action of striatal cholinergic-GABAergic microcircuits conditions the subsequent GABA inhibitory shift

Communications Biology, 2023
Cholinergic interneurons of the striatum play a role in action selection and associative learning by activating local GABAergic inhibitory microcircuits.
Natalia Lozovaya, Sanaz Eftekhari, Constance Hammond   +2 more
doaj   +1 more source