Results 21 to 30 of about 179,337 (237)

Corticofugal GABAergic projection neurons in the mouse frontal cortex

open access: yesFrontiers in Neuroanatomy, 2015
Cortical projection neurons are classified by hodology in corticocortical, commissural and corticofugal subtypes. Although cortical projection neurons had been regarded as only glutamatergic neurons, recently corticocortical GABAergic projection neurons ...
Ryohei eTomioka   +2 more
doaj   +1 more source

NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]

open access: yes, 2011
Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Felmy, Felix   +3 more
core   +1 more source

Turning a Negative into a Positive: Ascending GABAergic Control of Cortical Activation and Arousal

open access: yesFrontiers in Neurology, 2015
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain. Recent technological advances have illuminated the role of GABAergic neurons in control of cortical arousal and sleep.
Ritchie Edward Brown, James Tim McKenna
doaj   +1 more source

In silico prediction and in vivo testing of promoters targeting GABAergic inhibitory neurons

open access: yesMolecular Therapy: Methods & Clinical Development, 2023
Impairment of GABAergic inhibitory neuronal function is linked to epilepsy and other neurological and psychiatric disorders. Recombinant adeno-associated virus (rAAV)-based gene therapy targeting GABAergic neurons is a promising treatment for GABA ...
Yosuke Niibori   +4 more
doaj   +1 more source

New insights into the classification and nomenclature of cortical GABAergic interneurons. [PDF]

open access: yes, 2013
A systematic classification and accepted nomenclature of neuron types is much needed but is currently lacking. This article describes a possible taxonomical solution for classifying GABAergic interneurons of the cerebral cortex based on a novel, web ...
A Karagiannis   +82 more
core   +2 more sources

Coincident glutamatergic depolarizations enhance GABAA receptor-dependent Cl- influx in mature and suppress Cl- efflux in immature neurons.

open access: yesPLoS Computational Biology, 2021
The impact of GABAergic transmission on neuronal excitability depends on the Cl--gradient across membranes. However, the Cl--fluxes through GABAA receptors alter the intracellular Cl- concentration ([Cl-]i) and in turn attenuate GABAergic responses, a ...
Aniello Lombardi   +3 more
doaj   +1 more source

Cortical GABAergic Neurons: Stretching It [PDF]

open access: yesFrontiers in Neuroanatomy, 2012
Peer ...
Rockland, Kathleen, DeFelipe, Javier
openaire   +5 more sources

Long-range GABAergic connections distributed throughout the neocortex and their possible function

open access: yesFrontiers in Neuroscience, 2010
Features and functions of long range GABAergic projection neurons in the developing cerebral cortex have been reported previously, although until now their significance in the adult cerebral cortex has remained uncertain. The septo-hippocampal circuit is
Nobuaki eTamamaki, Ryohei eTomioka
doaj   +1 more source

Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse [PDF]

open access: yes, 2003
We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket ...
Dean, I., Edwards, F.A., Robertson, S.J.
core   +3 more sources

Loss of IQSEC3 Disrupts GABAergic Synapse Maintenance and Decreases Somatostatin Expression in the Hippocampus

open access: yesCell Reports, 2020
Summary: Gephyrin interacts with various GABAergic synaptic proteins to organize GABAergic synapse development. Among the multitude of gephyrin-binding proteins is IQSEC3, a recently identified component at GABAergic synapses that acts through its ADP ...
Seungjoon Kim   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy