Results 31 to 40 of about 179,337 (237)

VIP-Expressing GABAergic Neurons: Disinhibitory vs. Inhibitory Motif and Its Role in Communication Across Neocortical Areas

Frontiers in Cellular Neuroscience, 2022
GABAergic neurons play a crucial role in shaping cortical activity. Even though GABAergic neurons constitute a small fraction of cortical neurons, their peculiar morphology and functional properties make them an intriguing and challenging task to study ...
Alfonso junior Apicella, Ivan Marchionni, Ivan Marchionni   +2 more
doaj   +1 more source

Distinct Translaminar Glutamatergic Circuits to GABAergic Interneurons in the Neonatal Auditory Cortex

Cell Reports, 2017
GABAergic activity is important in neocortical development and plasticity. Because the maturation of GABAergic interneurons is regulated by neural activity, the source of excitatory inputs to GABAergic interneurons plays a key role in development.
Rongkang Deng, Joseph P.Y. Kao, Patrick O. Kanold   +2 more
doaj   +1 more source

Hilar GABAergic interneuron activity controls spatial learning and memory retrieval. [PDF]

PLoS ONE, 2012
Although extensive research has demonstrated the importance of excitatory granule neurons in the dentate gyrus of the hippocampus in normal learning and memory and in the pathogenesis of amnesia in Alzheimer's disease (AD), the role of hilar GABAergic ...
Yaisa Andrews-Zwilling, Anna K Gillespie, Alexxai V Kravitz, Alexandra B Nelson, Nino Devidze, Iris Lo, Seo Yeon Yoon, Nga Bien-Ly, Karen Ring, Daniel Zwilling, Gregory B Potter, John L R Rubenstein, Anatol C Kreitzer, Yadong Huang   +13 more
doaj   +1 more source

Mechanisms of GABAergic Homeostatic Plasticity

Neural Plasticity, 2011
Homeostatic plasticity ensures that appropriate levels of activity are maintained through compensatory adjustments in synaptic strength and cellular excitability.
Peter Wenner
doaj   +1 more source

Disrupted GABAergic facilitation of working memory performance in people with schizophrenia. [PDF]

, 2020
ObjectivesGamma-Amiobutyric acid (GABA) is a primary inhibitory neurotransmitter that facilitates neural oscillations that coordinate neural activity between brain networks to facilitate cognition.
Carter, CS, Hurtado, MY, Lesh, TA, Maddock, RJ, Niendam, TA, Ragland, JD, Ranganath, C, Tanase, C   +7 more
core  

Interaction of hypothalamic GABA\u3csub\u3eA\u3c/sub\u3e and excitatory amino acid receptors controlling heart rate in rats [PDF]

, 1991
We have previously shown that microinjection of drugs that impair gamma-aminobutyric acid (GABA)-mediated synaptic inhibition into the dorsomedial hypothalamus (DMH) of rats generates cardiovascular and behavioral changes that mimic the response to ...
DiMicco, Joseph A., Soltis, Robert P.
core   +2 more sources

Acidosis-Induced Dysfunction of Cortical GABAergic Neurons through Astrocyte-Related Excitotoxicity.

PLoS ONE, 2015
BackgroundAcidosis impairs cognitions and behaviors presumably by acidification-induced changes in neuronal metabolism. Cortical GABAergic neurons are vulnerable to pathological factors and their injury leads to brain dysfunction.
Li Huang, Shidi Zhao, Wei Lu, Sudong Guan, Yan Zhu, Jin-Hui Wang   +5 more
doaj   +1 more source

The Lateral Hypothalamic and BNST GABAergic Projections to the Anterior Ventrolateral Periaqueductal Gray Regulate Feeding

Cell Reports, 2019
Summary: Overeating is a serious issue in modern society, causing many health problems, including obesity. Although the hypothalamus has been previously identified as the key brain structure that regulates body weight homeostasis, the downstream pathways
Sijia Hao, Hongbin Yang, Xiaomeng Wang, Yang He, Haifeng Xu, Xiaotong Wu, Libiao Pan, Yijun Liu, Huifang Lou, Han Xu, Huan Ma, Wang Xi, Yudong Zhou, Shumin Duan, Hao Wang   +14 more
doaj   +1 more source

NMDA receptors in GABAergic synapses during postnatal development. [PDF]

PLoS ONE, 2012
GABA (gamma-aminobutyric-acid), the main inhibitory neurotransmitter in the adult brain, exerts depolarizing (excitatory) actions during development and this GABAergic depolarization cooperates with NMDARs (N-methyl-D-aspartate receptors) to drive ...
Csaba Cserép, Eszter Szabadits, András Szőnyi, Masahiko Watanabe, Tamás F Freund, Gábor Nyiri   +5 more
doaj   +1 more source

Loss of FKBP5 Affects Neuron Synaptic Plasticity: An Electrophysiology Insight [PDF]

, 2019
FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR.
Deng, Ran, Dou, Longyu, Liang, Tiebing, Liu, Ming, Qiu, Bin, Ren, Wei, Shou, Weinian, Stewart, Robert B., Wang, Chao, Wang, Jun, Williams, Kent E., Xie, Zhongwen, Xu, Yuxue, Yong, Weidong, Zhao, Zhenwen   +14 more
core   +1 more source