Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease
Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed +7 more
wiley +1 more source
Multiple layers of diversity govern the cell type specificity of GABAergic input received by mouse subicular pyramidal neurons [PDF]
Nancy Castro Borjas +2 more
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Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz +10 more
wiley +1 more source
Cortical GABAergic Neuron Dysregulation in Schizophrenia Is Age Dependent. [PDF]
Kiss D +8 more
europepmc +1 more source
The Dynamic Regulation of GABAergic Synapses Affects Cell Growth and Structural Plasticity of Adult-born Neurons [PDF]
Francine Deprez
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The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie +5 more
wiley +1 more source
Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity. [PDF]
Chan F +12 more
europepmc +1 more source
Adenosine Inhibits the Excitatory Synaptic Inputs to Basal Forebrain Cholinergic, GABAergic, and Parvalbumin Neurons in Mice [PDF]
Chun Yang +2 more
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