Results 181 to 190 of about 759,534 (341)

Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed   +7 more
wiley   +1 more source

Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development

open access: yesDevelopment, 2012
V. Baubet   +5 more
semanticscholar   +1 more source

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

open access: yesChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz   +10 more
wiley   +1 more source

Cortical GABAergic Neuron Dysregulation in Schizophrenia Is Age Dependent. [PDF]

open access: yesBiol Psychiatry Glob Open Sci
Kiss D   +8 more
europepmc   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

open access: yesPediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie   +5 more
wiley   +1 more source

Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity. [PDF]

open access: yesJ Neurochem
Chan F   +12 more
europepmc   +1 more source

Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons

open access: gold
Amy N. Shore   +8 more
openalex   +1 more source

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