Results 221 to 230 of about 786,405 (284)

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun   +6 more
wiley   +1 more source

GABAergic neurons in the ventral tegmental area represent and regulate force vectors. [PDF]

open access: yesCell Rep
Jiang Q   +5 more
europepmc   +1 more source

Restoring failed inhibition in the substantia nigra pars reticulata suppresses absence seizures in rats

open access: yesEpilepsia, EarlyView.
Abstract Objective For over four decades, the substantia nigra pars reticulata (SNr) has been recognized as a critical structure in the modulation of seizure activity. Pharmacological and optogenetic inhibition of the SNr produces robust seizure suppression in a range of seizure models.
Devin Palmer, Patrick A. Forcelli
wiley   +1 more source

Ethanol Enhances GABAergic Transmission Onto Dopamine Neurons in the Ventral Tegmental Area of the Rat

open access: green, 2008
Jonathan W. Theile   +3 more
openalex   +1 more source

Spreading depolarization and its influence on epileptiform activity

open access: yesEpilepsia, EarlyView.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque   +2 more
wiley   +1 more source

Ventral Pallidal GABAergic Neurons Drive Consumption in Male, But Not Female, Rats. [PDF]

open access: yeseNeuro
Scott A   +7 more
europepmc   +1 more source

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease

open access: yesEpilepsia, EarlyView.
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa   +17 more
wiley   +1 more source

Rebound Bursts in GABAergic Neurons of the Thalamic ReticularNucleus in Postnatal Mice

open access: gold, 2010
X Wang   +5 more
openalex   +1 more source

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