Results 221 to 230 of about 546,048 (293)

Annual Research Review: A probe into sensitive periods – how the developmental timing of adverse childhood experiences influences brain structure and function – a systematic review

Journal of Child Psychology and Psychiatry, EarlyView.
It is proposed that adverse childhood experiences (ACEs) – potent predictors of mental illness – exert time‐dependent effects on neurodevelopment, reflecting periods of heightened neuroplasticity and developmental sensitivity. We systematically reviewed neuroimaging studies examining the role of timing in the association of ACE exposure with brain ...
Stephanie Hartanto, Divyangana Rakesh, Catherine Orr, Ebony Forlano, Muskan Khetan, Sarah Whittle   +5 more
wiley   +1 more source

Transcriptomic insights into fate choice of pallial versus subpallial GABAergic neurons. [PDF]

Nat Commun
Sun L, Xiong F, Huang F, Dong S, Zhu P, Jiang P, Zhang B, Zhang X, Sun J, Peng H, Zhao C.   +10 more
europepmc   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington's disease models. [PDF]

Transl Neurodegener
Di Franco N, Bengoetxea de Tena I, Sanchez-Ruiz A, Pereda-Velarde A, Enfedaque F, Gónzalez-Arias C, Rio LMM, Bortolozzi A, Rodriguez-Puertas R, Costas-Insua C, Molina-Porcel L, Vazquez-Oliver A, Ozaita A, Guzmán M, Perea G, Ginés S.   +15 more
europepmc   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

Journal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó, Veronika Sigutova, Anna M. Schneider, Anna Hoerder‐Suabedissen, Zoltán Molnár   +4 more
wiley   +1 more source

RHO GTPase by L1 GABAergic neurons in frontal cortex and L6 glutamatergic neurons in prefrontal cortex differentiates states of unconsciousness. [PDF]

Sci Rep
Taguchi YH, Turki T.
europepmc   +1 more source

Orchestrated molecular changes of proliferative, migratory‐fibrillar, synaptic, and postmigratory compartments align with precocious cortex‐type specification in the early human pallium

Journal of Anatomy, EarlyView.
Early human cortical development is organized by transient cellular compartments that define cortical types before mature layers form. Analysis of the human fetal pallium (7.5–15 PCW) shows distinct spatiotemporal trajectories for the archicortex, mesocortex, and neocortex, with delayed but accelerated differentiation in allocortical regions.
Janja Kopić, Fran Božić, Alisa Junaković Munjas, Željka Krsnik, Ivica Kostović   +4 more
wiley   +1 more source

GABAergic neurons are a key cell type in a <i>Drosophila</i> model of PARK14/<i>PLA2G6</i>-associated neurodegeneration. [PDF]

Front Neurosci
Meimoun NS, Benji S, Besharim WZ, Cantor YY, Carroll ES, Coplin BI, Davidovics MB, Gerber M, Hirschprung PM, Jacobson EI, Levenbrown AL, Levitt DT, Levy A, Mazin YZ, Moskowitz AD, Purow JI, Rimberg A, Rothstein JE, Saks EY, Saperstein R, Scher YY, Schwarcz YD, Silver M, Stein YF, Wiener YY, Steinhauer J.   +25 more
europepmc   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

A cell-autonomous role for the vitamin B6 metabolism gene <i>PNPO</i> in <i>Drosophila</i> GABAergic neurons. [PDF]

J Neurogenet
Fu W, Landaverde S, Zhuang X, Iyengar A.
europepmc   +1 more source