Results 11 to 20 of about 10,211 (179)

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

Hepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara   +29 more
wiley   +1 more source

Portal hypertension may influence the registration of hypointensity of small hepatocellular carcinoma in the hepatobiliary phase in gadoxetic acid MR

Radiology and Oncology, 2022
The aim of the study was to analyze the association between the liver uptake of Gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid (Gd-EOB-DTPA) in the hepatobiliary phase (HBP) in cirrhotic patients and the presence of clinically significant ...
Caparroz Carla, Forner Alejandro, Rimola Jordi, Darnell Anna, García-Criado Ángeles, Ayuso Juan Ramón, Reig María, Bruix Jordi, Ayuso Carmen   +8 more
doaj   +1 more source

A Novel Paramagnetic Substrate for Detecting Myeloperoxidase Activity in Vivo

Molecular Imaging, 2012
Bis-phenylamides and bis-hydroxyindolamides of diethylenetriaminepentaacetic acid-gadolinium (DTPA(Gd)) are paramagnetic reducing substrates of peroxidases that enable molecular imaging of peroxidase activity in vivo. Specifically, gadolinium chelates of
Mohammed S. Shazeeb, Yang Xie, Suresh Gupta, Alexei A. Bogdanov   +3 more
doaj   +1 more source

Perbedaan Intensitas Penyengatan Meningeal Hasil MRI antara Sekuens T2 FLAIR Post Contrast dan T1WI Post Contrast Gadolinium-DTPA dalam Mendeteksi Penyangatan Meningeal pada Kasus Meningitis Tuberkulosis

Majalah Kedokteran Bandung, 2017
Diagnosis meningitis TB terutama pada kasus possible dan probable sulit ditegakkan. Pemeriksaan MRI kepala dengan kontras Gadolinium-DTPA adalah modalitas radiologi yang paling sensitif untuk membantu mendiagnosis penyakit ini.
Arie Hendarin, Rista D. Soetikno, Harry Galuh Nugraha   +2 more
doaj   +1 more source

Construction of ultrasmall gold nanoparticles based contrast agent via Host-Guest interaction for Tumor-targeted magnetic resonance imaging

Materials & Design, 2022
In order to overcome the shortcomings of small-molecule contrast agents (CAs) in clinic, gadolinium-based CAs have attracted increasingly interesting in tumor diagnosis.
Yiwei Zhang, Xinxin Li, Xing Chen, Yingfan Zhang, Yun Deng, Yanhua Yu, Bing Wang, Yanan Xue, Yulun Huang, Min Liu   +9 more
doaj   +1 more source

Accuracy of tumor perfusion assessment in Rat C6 gliomas model with USPIO

Open Medicine, 2019
Detailed characterization of the permeability and vascular volume of brain tumor vasculature can provide essential insights into tumor physiology.
Yu Xiang-Rong, Cao Bo-Ling, Li Wei, Tian Ye, Du Zhong-Li   +4 more
doaj   +1 more source

MRI detection of endolymphatic hydrops in Meniere's disease in 8 minutes using MIIRMR and a 20-channel coil after targeted gadolinium delivery

World Journal of Otorhinolaryngology-Head and Neck Surgery, 2019
Background: Endolymphatic hydrops (EH) become visible in vertigo patients, particularly in those with Meniere's disease (MD), in vivo using gadolinium-enhanced MRI.
Jing Zou, Zhen Wang, Yukun Chen, Guoping Zhang, Luguang Chen, Jianping Lu   +5 more
doaj   +1 more source

Pathological mechanism for delayed hyperenhancement of chronic scarred myocardium in contrast agent enhanced magnetic resonance imaging. [PDF]

PLoS ONE, 2014
OBJECTIVES: To evaluate possible mechanism for delayed hyperenhancement of scarred myocardium by investigating the relationship of contrast agent (CA) first pass and delayed enhancement patterns with histopathological changes.
Jian Wang, Bo Xiang, Hung-Yu Lin, Hongyu Liu, Darren Freed, Rakesh C Arora, Ganghong Tian   +6 more
doaj   +1 more source

Commentary on “A Microfluidic Platform to Design Crosslinked Hyaluronic Acid Nanoparticles (cHANPs) for Enhanced MRI”

Molecular Imaging, 2017
Strategies to enhance the relaxometric properties of gadolinium (Gd)-based contrast agents (CAs) for magnetic resonance imaging (MRI), without the chemical modification of chelates, have recently had a strong impact on the diagnostic field. We have taken
Maria Russo PhD, Paolo Bevilacqua PhD, Paolo Antonio Netti PhD, Enza Torino PhD   +3 more
doaj   +1 more source

Health economic assessment of Gd-EOB-DTPA MRI versus ECCM-MRI and multi-detector CT for diagnosis of hepatocellular carcinoma in China.

PLoS ONE, 2018
Limited data exists in China on the comparative cost of gadolinium ethoxybenzyl diethylenetriamine magnetic resonance imaging (Gd-EOB-DTPA-MRI) with other imaging techniques.
Xiaoning He, Jing Wu, Anke-Peggy Holtorf, Harald Rinde, Shuangshuang Xie, Wen Shen, Jiancun Hou, Xuehua Li, Ziping Li, Jiaming Lai, Yuting Wang, Lin Zhang, Jian Wang, Xuesong Li, Kuansheng Ma, Feng Ye, Han Ouyang, Hong Zhao   +17 more
doaj   +1 more source