Results 31 to 40 of about 11,313 (223)

Accuracy of tumor perfusion assessment in Rat C6 gliomas model with USPIO

Open Medicine, 2019
Detailed characterization of the permeability and vascular volume of brain tumor vasculature can provide essential insights into tumor physiology.
Yu Xiang-Rong, Cao Bo-Ling, Li Wei, Tian Ye, Du Zhong-Li   +4 more
doaj   +1 more source

DNA‐Induced Entropic Gain Triggers an Allosteric Switch for Biomolecular Condensation of Heat Shock Transcription Factor 1

Angewandte Chemie, EarlyView.
Hsf1 undergoes phase separation around target DNA, activating stress‐responsive transcription. DNA binding tunes conformational dynamics of Hsf1DBD, which propagates through large‐scale domain rearrangements involving DBD–IDR interactions to regulate phase separation. This hierarchical framework illustrates how local structural events at the side chain
Soichiro Kawagoe, Hiroyuki Kumeta, Tomohide Saio   +2 more
wiley   +2 more sources

Pathological mechanism for delayed hyperenhancement of chronic scarred myocardium in contrast agent enhanced magnetic resonance imaging. [PDF]

PLoS ONE, 2014
OBJECTIVES: To evaluate possible mechanism for delayed hyperenhancement of scarred myocardium by investigating the relationship of contrast agent (CA) first pass and delayed enhancement patterns with histopathological changes.
Jian Wang, Bo Xiang, Hung-Yu Lin, Hongyu Liu, Darren Freed, Rakesh C Arora, Ganghong Tian   +6 more
doaj   +1 more source

Commentary on “A Microfluidic Platform to Design Crosslinked Hyaluronic Acid Nanoparticles (cHANPs) for Enhanced MRI”

Molecular Imaging, 2017
Strategies to enhance the relaxometric properties of gadolinium (Gd)-based contrast agents (CAs) for magnetic resonance imaging (MRI), without the chemical modification of chelates, have recently had a strong impact on the diagnostic field. We have taken
Maria Russo PhD, Paolo Bevilacqua PhD, Paolo Antonio Netti PhD, Enza Torino PhD   +3 more
doaj   +1 more source

Neutral gadolinium(III) complexes of bulky octadentate dtpa derivatives as potential contrast agents for magnetic resonance imaging

, 1995
A series of bulky and neutral gadolinium complexes of [bis(R-amide)dtpaH3] (where R = Pri,, Bui,, Bz and phenylethyl, L1--L4)) with potential application as contrast agents for magnetic resonance imaging has been prepared and characterized ; the ...
Scowen, I.J., McPartlin, M., Chowdhury, A.H.M.S., Bligh, S.W.A.   +3 more
core   +1 more source

Health economic assessment of Gd-EOB-DTPA MRI versus ECCM-MRI and multi-detector CT for diagnosis of hepatocellular carcinoma in China.

PLoS ONE, 2018
Limited data exists in China on the comparative cost of gadolinium ethoxybenzyl diethylenetriamine magnetic resonance imaging (Gd-EOB-DTPA-MRI) with other imaging techniques.
Xiaoning He, Jing Wu, Anke-Peggy Holtorf, Harald Rinde, Shuangshuang Xie, Wen Shen, Jiancun Hou, Xuehua Li, Ziping Li, Jiaming Lai, Yuting Wang, Lin Zhang, Jian Wang, Xuesong Li, Kuansheng Ma, Feng Ye, Han Ouyang, Hong Zhao   +17 more
doaj   +1 more source

OATP1B3 Expression in Hepatocellular Carcinoma Correlates with Intralesional Gd-EOB-DTPA Uptake and Signal Intensity on Gd-EOB-DTPA-Enhanced MRI

Cancer Management and Research, 2021
Xiaojiao Zhou, Liling Long, Zhiqing Mo, Yajuan Li Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, People’s Republic of ChinaCorrespondence: Liling LongDepartment of Radiology, The First ...
Zhou X, Long L, Mo Z, Li Y
doaj  

Synthesis and Physicochemical Characterization of a New Gadolinium Chelate:  The Liver-Specific Magnetic Resonance Imaging Contrast Agent Gd-EOB-DTPA

, 2016
A convenient synthesis of disodium S-[4-(4-ethoxybenzyl)-3,6,9-tris[(carboxy-κO)methyl]-3,6,9-triazaundecandioato)(5-)-κ3N3,N6,N9,κ2O1,O11]gadolinate(2-) (Gd-EOB-DTPA), 1, is reported. This water-soluble complex is presently undergoing phase III clinical
H. Schmitt-Willich (2978094), J. Platzek (2974509), M. Brehm (2978091), D. Sülzle (2974503), B. Radüchel (2974497), A. Müller-Fahrnow (2974518), G. Michl (2974512), Ch. L. J. Ewers (2978088), O. Petrov (2978097)   +8 more
core   +1 more source

Inflammation-Specific T Imaging Using Anti-Intercellular Adhesion Molecule 1 Antibody-Conjugated Gadolinium Diethylenetriaminepentaacetic Acid

Molecular Imaging, 2007
To examine inflammatory tissue, an initial and common symptom of various types of pathogenesis, we designed inflammation-targeted T 1 contrast agents prepared by bioconjugation of gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) with anti ...
Kyu-Sil Choi, Sun-Hee Kim, Quan-Yu Cai, Soo-Yeon Kim, Hyang-Ok Kim, Hye-Jin Lee, Eun-A Kim, Seong-Eon Yoon, Ki-Jung Yun, Kwon-Ha Yoon   +9 more
doaj   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source