Results 31 to 40 of about 10,211 (179)

In-vitro gadolinium retro-microdialysis in agarose gel—a human brain phantom study

Frontiers in Radiology
Rationale and objectivesCerebral microdialysis is a technique that enables monitoring of the neurochemistry of patients with significant acquired brain injury, such as traumatic brain injury (TBI) and subarachnoid haemorrhage (SAH).
Chisomo Zimphango, Marius O. Mada, Marius O. Mada, Stephen J. Sawiak, Stephen J. Sawiak, Susan Giorgi-Coll, T. Adrian Carpenter, Peter J. Hutchinson, Peter J. Hutchinson, Keri L. H. Carpenter, Keri L. H. Carpenter, Matthew G. Stovell, Matthew G. Stovell   +12 more
doaj   +1 more source

In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model

BMC Cancer, 2011
Background Pancreatic cancer is the fourth leading cause of tumour death in the western world. However, appropriate tumour models are scarce. Here we present a syngeneic murine pancreatic cancer model using 7 Tesla MRI and evaluate its clinical relevance
Hadlich Stefan, Lerch Markus M, Mayerle Julia, Weiss Ulrich F, Kuehn Sandra, Diedrich Stephan, Seubert Florian, Roese Sebastian, Speerforck Sven, Kühn Jens-P, Albers Nele, Sendler Matthias, Kaeding André, Partecke Ivo L, Hosten Norbert, Heidecke Claus-D, Puls Ralf, von Bernstorff Wolfram   +17 more
doaj   +1 more source

Effect of Visualized Respiratory Training on Patient Cooperation and Image Quality in Gadoxetic Acid Disodium‐Enhanced Liver MRI: A Randomized Controlled Trial

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Respiratory motion artifacts impair diagnostic accuracy in gadoxetic acid disodium (Gd‐EOB‐DTPA)‐enhanced liver MRI. Conventional verbal pre‐scan breathing training often yields inconsistent patient cooperation and image quality, creating an urgent clinical need for optimized training methods.
Li Mei, Xin Luo, Bingyan Wang, Junfeng Wang, Chao Huang, Xuemei Hu, Qin Li, Wenyan Zhang   +7 more
wiley   +1 more source

Impact of pre‐examination video education in Gd‐EOB‐DTPA‐enhanced liver MRI: A comparative study

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 34-41, March 2025.
This study evaluates the effects of pre‐examination video education on patient anxiety, satisfaction and image quality in Gd‐EOB‐DTPA‐enhanced liver MRI. We found that video education significantly reduced anxiety, increased patient satisfaction and improved image quality compared to standard pre‐MRI guidance, highlighting the potential of video ...
Hongfang Huang, Chenhui Li, Zisan Zeng, Junli Liang   +3 more
wiley   +1 more source

Biocompatible Nanocomplexes for Molecular Targeted MRI Contrast Agent

Nanoscale Research Letters, 2009
Accurate diagnosis in early stage is vital for the treatment of Hepatocellular carcinoma. The aim of this study was to investigate the potential of poly lactic acid–polyethylene glycol/gadolinium–diethylenetriamine-pentaacetic acid (PLA–
Yu Dexin, Ma Chunhong, Wang Shaojie, Lu Zaijun, Chen Zhijin, Zhang Na   +5 more
doaj   +1 more source

Dynamic Contrast-Enhanced Magnetic Resonance Imaging with Gd-EOB-DTPA for the Evaluation of Liver Fibrosis Induced by Carbon Tetrachloride in Rats. [PDF]

PLoS ONE, 2015
To investigate the utility of dynamic contrast-enhanced MRI (DCE-MRI) with Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) for detecting liver fibrosis induced by carbon tetrachloride (CCl4) in rats.This study was approved by ...
Wei Zhang, Xiang Kong, Zhen J Wang, Song Luo, Wei Huang, Long Jiang Zhang   +5 more
doaj   +1 more source

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

Visualization of Chronic Myocardial Infarction Using the Intravascular Contrast Agent MS-325 (Gadofosveset) in Patients

The Scientific World Journal, 2012
Aims. The aim of this study was to evaluate the potential of visualizing chronic myocardial infarction in patients using the intravascular CA MS-325 (gadofosveset, EPIX Pharmaceuticals, Mass, USA). Methods. Nine patients were enrolled in a clinical phase
Thomas Thouet, Bernhard Schnackenburg, Thomas Kokocinski, Eckart Fleck, Eike Nagel, Sebastian Kelle   +5 more
doaj   +1 more source

Brain Clearance of Contrast Agent in Intravenous DCE‐MRI Is Measurable and Cannot Be Explained by Clearance Across the BBB Alone

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To determine the feasibility of measuring brain clearance of gadolinium contrast agent using standard intravenous DCE‐MRI acquisitions and evaluate the contribution of blood–brain barrier (BBB) and non‐BBB clearance routes. Methods Uptake and extended Tofts models were fit to DCE‐MRI data from people with Parkinson's disease, post ...
Martin Kozár, Ioana‐Emilia Mosneag, Sarah Al‐Bachari, Igor Chernyavsky, Geoff J. M. Parker, Hervé Boutin, Laura M. Parkes, Ingo Schiessl, Ben R. Dickie   +8 more
wiley   +1 more source

r1 and r2 Relaxivities of Dendrons Based on a OEG-DTPA Architecture: Effect of Gd3+ Placement and Dendron Functionalization

Journal of Nanotechnology, 2015
In magnetic resonance imaging, contrast agents are employed to enhance the signal intensity. However, current commercial contrast agents are hindered by a low relaxivity constant.
Peter Fransen, Daniel Pulido, Lorena Simón-Gracia, Ana Paula Candiota, Carles Arús, Fernando Albericio, Miriam Royo   +6 more
doaj   +1 more source