Results 51 to 60 of about 11,313 (223)

In-vitro gadolinium retro-microdialysis in agarose gel—a human brain phantom study

Frontiers in Radiology
Rationale and objectivesCerebral microdialysis is a technique that enables monitoring of the neurochemistry of patients with significant acquired brain injury, such as traumatic brain injury (TBI) and subarachnoid haemorrhage (SAH).
Chisomo Zimphango, Marius O. Mada, Marius O. Mada, Stephen J. Sawiak, Stephen J. Sawiak, Susan Giorgi-Coll, T. Adrian Carpenter, Peter J. Hutchinson, Peter J. Hutchinson, Keri L. H. Carpenter, Keri L. H. Carpenter, Matthew G. Stovell, Matthew G. Stovell   +12 more
doaj   +1 more source

In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model

BMC Cancer, 2011
Background Pancreatic cancer is the fourth leading cause of tumour death in the western world. However, appropriate tumour models are scarce. Here we present a syngeneic murine pancreatic cancer model using 7 Tesla MRI and evaluate its clinical relevance
Hadlich Stefan, Lerch Markus M, Mayerle Julia, Weiss Ulrich F, Kuehn Sandra, Diedrich Stephan, Seubert Florian, Roese Sebastian, Speerforck Sven, Kühn Jens-P, Albers Nele, Sendler Matthias, Kaeding André, Partecke Ivo L, Hosten Norbert, Heidecke Claus-D, Puls Ralf, von Bernstorff Wolfram   +17 more
doaj   +1 more source

Gadolinium-Based Contrast Agents and Free Gadolinium Inhibit Differentiation and Activity of Bone Cell Lineages. [PDF]

OBJECTIVES Administration of gadolinium-based contrast agents (GBCA) in magnetic resonance imaging results in the long-term retention of gadolinium (Gd) in tissues and organs, including the bone, and may affect their function and metabolism.
Hofstetter, Wilhelm, Stähli, Christoph, Strunz, Franziska, Egli, Rainer J, Heverhagen, Johannes T   +4 more
core   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

iRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li, Aiyan Ji, Qihang Ding, Hongyue Lou, Zhen Cheng   +4 more
wiley   +1 more source

Heterobimetallic gadolinium(III)-iron(III) complex of DTPA-bis(3-hydroxytyramide)

, 2004
A derivative of diethylenetriamine-N,N,N',N",N"-pentaacetic acid (DTPA), carrying two catechol functional groups has been synthesised by the reaction between DTPA-bis(anhydride) and 3-hydroxytyramine (dopamine).
Parac-Vogt, Tatjana, Kimpe, Kristof, Binnemans, Koen   +2 more
core   +1 more source

Biocompatible Nanocomplexes for Molecular Targeted MRI Contrast Agent

Nanoscale Research Letters, 2009
Accurate diagnosis in early stage is vital for the treatment of Hepatocellular carcinoma. The aim of this study was to investigate the potential of poly lactic acid–polyethylene glycol/gadolinium–diethylenetriamine-pentaacetic acid (PLA–
Yu Dexin, Ma Chunhong, Wang Shaojie, Lu Zaijun, Chen Zhijin, Zhang Na   +5 more
doaj   +1 more source

Dynamic Contrast-Enhanced Magnetic Resonance Imaging with Gd-EOB-DTPA for the Evaluation of Liver Fibrosis Induced by Carbon Tetrachloride in Rats. [PDF]

PLoS ONE, 2015
To investigate the utility of dynamic contrast-enhanced MRI (DCE-MRI) with Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) for detecting liver fibrosis induced by carbon tetrachloride (CCl4) in rats.This study was approved by ...
Wei Zhang, Xiang Kong, Zhen J Wang, Song Luo, Wei Huang, Long Jiang Zhang   +5 more
doaj   +1 more source

Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross‐Sectional Study Using Cardiac MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Antiretroviral therapy has transformed HIV into a chronic condition, yet cardiac injury remains a major issue. Purpose To assess the ability of cardiac MR imaging markers to predict cardiac injury and disease progression in HIV‐infected individuals. Study Type Prospective.
Chunyan Deng, Wei Sun, Tianhu Gao, Haixia Chen, Lu Liu, Ran Li   +5 more
wiley   +1 more source

Visualization of Chronic Myocardial Infarction Using the Intravascular Contrast Agent MS-325 (Gadofosveset) in Patients

The Scientific World Journal, 2012
Aims. The aim of this study was to evaluate the potential of visualizing chronic myocardial infarction in patients using the intravascular CA MS-325 (gadofosveset, EPIX Pharmaceuticals, Mass, USA). Methods. Nine patients were enrolled in a clinical phase
Thomas Thouet, Bernhard Schnackenburg, Thomas Kokocinski, Eckart Fleck, Eike Nagel, Sebastian Kelle   +5 more
doaj   +1 more source

Effect of Visualized Respiratory Training on Patient Cooperation and Image Quality in Gadoxetic Acid Disodium‐Enhanced Liver MRI: A Randomized Controlled Trial

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Respiratory motion artifacts impair diagnostic accuracy in gadoxetic acid disodium (Gd‐EOB‐DTPA)‐enhanced liver MRI. Conventional verbal pre‐scan breathing training often yields inconsistent patient cooperation and image quality, creating an urgent clinical need for optimized training methods.
Li Mei, Xin Luo, Bingyan Wang, Junfeng Wang, Chao Huang, Xuemei Hu, Qin Li, Wenyan Zhang   +7 more
wiley   +1 more source