Results 21 to 30 of about 149 (148)

Redistribution of flexibility in stabilizing antibody fragment mutants follows Le Châtelier's principle. [PDF]

open access: yesPLoS ONE, 2014
Le Châtelier's principle is the cornerstone of our understanding of chemical equilibria. When a system at equilibrium undergoes a change in concentration or thermodynamic state (i.e., temperature, pressure, etc.), La Châtelier's principle states that an ...
Tong Li   +5 more
doaj   +1 more source

A Fully Integrated Sensor SoC with Digital Calibration Hardware and Wireless Transceiver at 2.4 GHz

open access: yesSensors, 2013
A single-chip sensor system-on-a-chip (SoC) that implements radio for 2.4 GHz, complete digital baseband physical layer (PHY), 10-bit sigma-delta analog-to-digital converter and dedicated sensor calibration hardware for industrial sensing systems has ...
Dong-Sun Kim   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A 250 °C Low-Power, Low-Temperature-Drift Offset Chopper-Stabilized Operational Amplifier with an SC Notch Filter for High-Temperature Applications

open access: yesApplied Sciences
This paper proposes a three-stage op amp based on the SOI (silicon-on-insulator) process, which achieves a low offset voltage and temperature coefficient across a wide temperature range from −40 °C to 250 °C.
Zhong Yang   +5 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Mathematical modelling and compensation strategies for printing dot gain.

open access: yesPLoS ONE
In contemporary printing processes, dot gain is a pivotal factor influencing print quality. This phenomenon, characterized by the loss of image details and the potential for chromatic aberration, poses significant challenges to enhancing print quality ...
Xiaoli Liu, Bingzhong Qiu, Ying-Leh Ling
doaj   +1 more source

Real-Time Wide-Range Carrier Frequency Offset Compensation by Multi-Thread PADE for Fully Softwarized Access Networks

open access: yesIEEE Access
With the evolution of access systems by network function virtualization (NFV) and the software-defined network (SDN), further softwarization including transmission functions is required in order to fully utilize the advantages that softwarization offers ...
Takahiro Suzuki   +3 more
doaj   +1 more source

Low-Noise Chopper-Stabilized Multi-Path Operational Amplifier with Nested Miller Compensation for High-Precision Sensors

open access: yesApplied Sciences, 2019
This paper presents a low-noise multi-path operational amplifier for high-precision sensors. A chopper stabilization technique is applied to the amplifier to remove offset and flicker noise.
Jaesung Kim   +7 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Implementation of Flat Gain Broadband Power Amplifier With Impedance Rotation Compensation

open access: yesIEEE Access, 2019
The conventional broadband impedance matching network in low-pass structure cannot present adequate broadband impedance rotation for the optimum broadband operation of the power amplifier (PA), resulting in performance variations and degradations.
Xiangyu Meng   +5 more
doaj   +1 more source

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