Results 61 to 70 of about 189,977 (232)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Intelligent Transducer for Temperature Measurement with Two-Wire or Three-Wire Platinum RTD

Sensors
The article presents an intelligent temperature transducer (ITT), which can work with a two-wire or a three-wire platinum resistance temperature detector (RTD). The ITT design allowed for compensation of the RTD’s lead wire resistance.
Wiesław Miczulski, Mariusz Krajewski, Sergiusz Sienkowski, Elżbieta Kawecka, Andrzej Perec   +4 more
doaj   +1 more source

Testing a Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

Arthritis Care &Research, EarlyView.
Objective We aimed to test the efficacy of personalized treatment of older veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABCs) as compared with usual care (UC). Methods Two hundred ninety‐nine veterans aged 65 to 89 with CLBP from three Veterans Affairs (VA) medical centers underwent baseline testing, randomization to ABC ...
Debra K. Weiner, Angela Gentili, Meika A. Fang, Edward Garay, Laura Lawson, Lenore Joseph, Cathy C. Lee, Michelle I. Rossi, Beverly Thorn, Subashan Perera   +9 more
wiley   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Current Tracking Adaptive Control of Brushless DC Motors

International Journal of Adaptive Control and Signal Processing, EarlyView.
In this paper, the current tracking for Brushless Direct Current motors is approached considering uncertainty in the parameters of the motor's model. An adaptive control scheme to compensate electrical parameters uncertainty is proposed without requiring any knowledge of the mechanical parameters.
Fernanda Ramos‐García, Axel Coronado‐Andrade, Gerardo Espinosa‐Pérez, Luis Alvarez‐Icaza   +3 more
wiley   +1 more source

Comb-based WDM transmission at 10 Tbit/s using a DC-driven quantum-dash mode-locked laser diode

, 2019
Chip-scale frequency comb generators have the potential to become key building blocks of compact wavelength-division multiplexing (WDM) transceivers in future metropolitan or campus-area networks.
Abderrahim Ramdane, Akrout, Anandarajah, Ataie, Calò, Christian Koos, Di Domenico, Fatadin, François Lelarge, Fülop, Godard, Godone, Hillerkuss, Hu, Huynh, Juned N. Kemal, Kamel Merghem, Kemal, Kikuchi, Lelarge, Leven, Lu, Magarini, Maldonado-Basilio, Marin-Palomo, Mercer, Moscoso-Mártir, Müller, Pablo Marin-Palomo, Pfau, Pfeifle, Pfeifle, Philipp Trocha, Pillai, Rodrigo-Navarro, Rosales, Rosales, Rosales, Savory, Schmogrow, Sebastian Randel, Stefan Wolf, Thompson, Torres-Company, Vedala, Winzer, Wolfgang Freude, Zhang   +47 more
core   +2 more sources

An Adaptive Human Pilot Model With Reaction Time Delay for Enhanced Adaptive Control in Piloted Systems

International Journal of Adaptive Control and Signal Processing, EarlyView.
This work introduces an adaptive human pilot model that captures pilot time‐delay effects in adaptive control systems. The model enables the prediction of pilot–controller interactions, facilitating safer integration and improved design of adaptive controllers for piloted applications.
Abdullah Habboush, Yildiray Yildiz
wiley   +1 more source

A 1.2-V, 106.4-dB DR Discrete-Time Sigma-Delta Modulator With Feedback Adaptive Cascaded Integrator for Sensor Applications

IEEE Access
This innovative research work introduces a novel second-order discrete-time Sigma-Delta ( $\Sigma \Delta $ ) Analog-to Digital Converter (ADC) design for high performance signal conditioning sensors.
Ghayur Hussain, Nguyen van Quang, Muhammad Basim, Chang Hyeon Kim, Nabeel Ahmad, Sung June Byun, Kang-Yoon Lee   +6 more
doaj   +1 more source

A prototype automatic phase compensation module [PDF]

The growing demands for high gain and accurate satellite communication systems will necessitate the utilization of large reflector systems. One area of concern of reflector based satellite communication is large scale surface deformations due to thermal ...
Terry, John D.
core   +1 more source