Results 121 to 130 of about 2,769,647 (318)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Assessment of Future Water Scarcity at Different Spatial and Temporal Scales of the Brahmaputra River Basin

open access: yes, 2014
Climate change is one of the main driving forces that affect both the temporal and spatial variability of water availability. Besides climatic change, current demographic trends, economic development and related land use changes have direct impact on ...
Gain A. K., Wada Y.
core   +1 more source

Gain-assisted chiral soliton microcombs

open access: yes, 2020
The emerging microresonator-based frequency combs revolutionize a broad range of applications from optical communications to astronomical calibration.
Teng Tan (1559365)   +10 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Material Structure Design of High-Gain and Low-Noise Multi-Gain-Stage Avalanche Photodiode

open access: yesPhotonics
In this work, the InGaAs/InAlAs multi-gain-stage APD model is established. The gain and the noise performance of multi-gain-stage APDs are analyzed based on DSMT.
Lihong Han   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gain-loss asymmetry in human experiential tasks

open access: yes, 2019
Prospect Theory models behaviour in one-off decisions where outcomes are described. Prospect Theory describes risk aversion when the choice is between gains and risk seeking when the choice is between losses.
Asgarova, Rana (11805131)   +1 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

VOR gain

open access: yes
This image reflects a graph of VOR ...

core  

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