Results 121 to 130 of about 904,948 (308)

Enhancing graph interpretation skills of Grade 9 students in learning microeconomics through I2 strategy

open access: yesIndonesian Journal of Education and Pedagogy
This action research aimed to enhance the graph interpretation skills of 35 Grade 9 Apitong students of Baybay National High School in learning microeconomics through the I2 strategy.
Jojenn P. Calingacion   +5 more
doaj   +1 more source

Spectral Properties of Dual Unit Gain Graphs

open access: yesSymmetry
In this paper, we study dual quaternion, dual complex unit gain graphs, and their spectral properties in a unified frame of dual unit gain graphs. Unit dual quaternions represent rigid movements in the 3D space, and have wide applications in robotics and computer graphics. Dual complex numbers have found application in brain science recently.
Chunfeng Cui   +3 more
openaire   +2 more sources

Relationships between cycle spaces, gain graphs, graph coverings, fundamental groups, path homology, and graph curvature

open access: yes, 2017
We prove a homology vanishing theorem for graphs with positive Bakry- mery curvature, analogous to a classic result of Bochner on manifolds \cite{Bochner}. Specifically, we prove that if a graph has positive curvature at every vertex, then its first homology group is trivial, where the notion of homology that we use for graphs is the path homology ...
Kempton, Mark   +2 more
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Graph neural network approach with spatial structure to anomaly detection of network data

open access: yesJournal of Big Data
Network anomaly detection using graph-structured data is a critical task in data mining and cybersecurity, involving the identification of unusual patterns within a network by analyzing its structure as a graph.
Hao Zhang   +5 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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