Results 121 to 130 of about 841,611 (282)
Biased graphs. I. Bias, balance, and gains
Journal of Combinatorial Theory, Series B, 1989 AbstractA biased graph is a graph together with a class of cirles (simple closed paths), called balanced, such that no theta subgraph contains exactly two balanced circles. A gain graph is a graph in which each edge has a gain (a label from a group so that reversing the direction inverts the gain); a circle is balanced if its edge gain product is 1 ...
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Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
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Cycle and circle tests of balance in gain graphs: Forbidden minors and their groups [PDF]
, 2005 Konstantin Rybnikov, Thomas Zasĺavsky
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Spectral Characterizations of Complex Unit Gain Graphs
, 2022 While eigenvalues of graphs are well studied, spectral analysis of complex unit gain graphs is still in its infancy. This thesis considers gain graphs whose gain groups are gradually less and less restricted, with the ultimate goal of classifying gain graphs that are characterized by their spectra. In such cases, the eigenvalues of a gain graph contain
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
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Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
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Indonesian Journal of Education and PedagogyThis action research aimed to enhance the graph interpretation skills of 35 Grade 9 Apitong students of Baybay National High School in learning microeconomics through the I2 strategy.
Jojenn P. Calingacion +5 more
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Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
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Graph neural network approach with spatial structure to anomaly detection of network data
Journal of Big DataNetwork anomaly detection using graph-structured data is a critical task in data mining and cybersecurity, involving the identification of unusual patterns within a network by analyzing its structure as a graph.
Hao Zhang +5 more
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