Results 111 to 120 of about 180,088 (293)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
PDASTSGAT: An STSGAT-Based Multipath Data Scheduling Algorithm
AlgorithmsHow to select the transmitting path in MPTCP scheduling is an important but open problem. This paper proposes an intelligent data scheduling algorithm using spatiotemporal synchronous graph attention neural networks to improve MPTCP scheduling.
Sen Xue, Chengyu Wu, Jing Han, Ao Zhan
doaj +1 more source
Distributed texture-based terrain synthesis
, 2011 Terrain synthesis is an important field of Computer Graphics that deals with the generation of 3D landscape models for use in virtual environments. The field has evolved to a stage where large and even infinite landscapes can be generated in realtime ...
Tasse, Flora Ponjou
core
Bounds and extremal graphs for the energy of complex unit gain graphs
Linear Algebra and its ApplicationsA complex unit gain graph ($ \mathbb{T} $-gain graph), $ Φ=(G, φ) $ is a graph where the gain function $ φ$ assigns a unit complex number to each orientation of an edge of $ G $ and its inverse is assigned to the opposite orientation. The associated adjacency matrix $ A(Φ) $ is defined canonically. The energy $ \mathcal{E}(Φ) $ of a $ \mathbb{T} $-gain
Aniruddha Samanta, M. Rajesh Kannan
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The \(\mathscr{G}\)-average of adjacency and Laplacian polynomials of a graph
The American Journal of CombinatoricsLet \(\mathscr{G}\) be a finite multiplicative group of quaternion unit \(U(\mathbb{H})\). The \(\mathscr{G}\)-average of adjacency (resp., Laplacian) polynomial of a graph \(G\) is defined as the arithmetic mean of the characteristic polynomials of
Yaoping Hou, Wenjun Xie
doaj +1 more source
Voxel-space shape grammars [PDF]
, 2012 The field of Procedural Generation is being increasingly used in modern content generation for its ability to significantly decrease the cost and time involved.
Crumley, Zacharia, Crumley, Mr. Zacharia
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Review on Graph Clustering and Subgraph Similarity Based Analysis of Neurological Disorders
, 2016 How can complex relationships among molecular or clinico-pathological entities of neurological disorders be represented and analyzed? Graphs seem to be the current answer to the question no matter the type of information: molecular data, brain images or ...
Jaya Thomas, 서동민, Lee Sael
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source