Results 51 to 60 of about 168,521 (260)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Occupancy probabilities in superintegrable bosonic networks

Nuclear Physics B
We associate a bosonic network to each complete bipartite graph. A Hamiltonian is defined with hopping terms on the edges of the graph, and a global interaction term depending on the vertex sets.
Lachlan Bennett, Angela Foerster, Phillip S. Isaac, Jon Links   +3 more
doaj   +1 more source

Collaborative Recommendation Based on Graph Neural Network Clustering Subgraphs Using Dual Graph Attention Network [PDF]

Jisuanji gongcheng
A recommendation system based on Graph Neural Network (GNN) can extract high-order connectivity between users and items. Collaborative Filtering (CF) is a classic recommendation algorithm that suffers from over-smoothing issues during the stacking of ...
XUE Yang, QIN Yao, ZHANG Shuxiang
doaj   +1 more source

Epistemic Network Analyses of Economics Students’ Graph Understanding: An Eye-Tracking Study

Sensors, 2020
Learning to solve graph tasks is one of the key prerequisites of acquiring domain-specific knowledge in most study domains. Analyses of graph understanding often use eye-tracking and focus on analyzing how much time students spend gazing at particular ...
Sebastian Brückner, Jan Schneider, Olga Zlatkin-Troitschanskaia, Hendrik Drachsler   +3 more
doaj   +1 more source

Integrating Knowledge Graphs into Distribution Grid Decision Support Systems

Future Internet, 2023
Distribution grids are complex networks containing multiple pieces of equipment. These components are interconnected, and each of them is described by various attributes.
Yashar Kor, Liang Tan, Petr Musilek, Marek Z. Reformat   +3 more
doaj   +1 more source

Distance matrices for conjugate skew gain graphs

Discrete Mathematics, Algorithms and Applications
A conjugate skew gain graph is a skew gain graph with the labels (also called, the conjugate skew gains) from the field of complex numbers on the oriented edges such that they get conjugated when we reverse the orientation. In this paper, we introduce distance matrices for conjugate skew gain graphs and characterize balanced conjugate skew gain graphs
K. Shahul Hameed, K. O. Ramakrishnan, K. Biju   +2 more
openaire   +3 more sources

On the Characteristic Polynomial of Skew Gain Graphs

, 2020
Gain graphs are graphs where the edges are given some orientation and labeled with the elements (called gains) from a group so that gains are inverted when we reverse the direction of the edges. Generalizing the notion of gain graphs, skew gain graphs have the property that the gain of a reversed edge is the image of edge gain under an anti-involution.
Hameed, K. S., Roy, Roshni T., Soorya, P., Germina, K. A.   +3 more
openaire   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

What can eye movements tell about students’ interpretations of contextual graphs? A methodological study on the use of the eye-mind hypothesis in the domain of functions

Frontiers in Education, 2022
IntroductionThe use of eye tracking (ET) in mathematics education research has increased in recent years. Eye tracking is a promising research tool in the domain of functions, especially in graph interpretation. It promises to gain insights into learners’
Aylin Thomaneck, Maike Vollstedt, Maike Schindler   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source