Results 61 to 70 of about 3,761,116 (301)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Epistemic Network Analyses of Economics Students’ Graph Understanding: An Eye-Tracking Study

Sensors, 2020
Learning to solve graph tasks is one of the key prerequisites of acquiring domain-specific knowledge in most study domains. Analyses of graph understanding often use eye-tracking and focus on analyzing how much time students spend gazing at particular ...
Sebastian Brückner, Jan Schneider, Olga Zlatkin-Troitschanskaia, Hendrik Drachsler   +3 more
doaj   +1 more source

Integrating Knowledge Graphs into Distribution Grid Decision Support Systems

Future Internet, 2023
Distribution grids are complex networks containing multiple pieces of equipment. These components are interconnected, and each of them is described by various attributes.
Yashar Kor, Liang Tan, Petr Musilek, Marek Z. Reformat   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Free idempotent generated semigroups: The word problem and structure via\n gain graphs [PDF]

, 2020
Igor Dolinka
openalex   +2 more sources

Occupancy probabilities in superintegrable bosonic networks

Nuclear Physics B
We associate a bosonic network to each complete bipartite graph. A Hamiltonian is defined with hopping terms on the edges of the graph, and a global interaction term depending on the vertex sets.
Lachlan Bennett, Angela Foerster, Phillip S. Isaac, Jon Links   +3 more
doaj   +1 more source

What can eye movements tell about students’ interpretations of contextual graphs? A methodological study on the use of the eye-mind hypothesis in the domain of functions

Frontiers in Education, 2022
IntroductionThe use of eye tracking (ET) in mathematics education research has increased in recent years. Eye tracking is a promising research tool in the domain of functions, especially in graph interpretation. It promises to gain insights into learners’
Aylin Thomaneck, Maike Vollstedt, Maike Schindler   +2 more
doaj   +1 more source

Inertia indices of a complex unit gain graph in terms of matching number [PDF]

, 2021
Yong Lu, Qi Wu
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source