Results 41 to 50 of about 6,069 (180)

From meadows to milk to mucosa – adaptation of Streptococcus and Lactococcus species to their nutritional environments [PDF]

, 2011
Lactic acid bacteria (LAB) are indigenous to food-related habitats as well as associated with the mucosal surfaces of animals. The LAB family Streptococcaceae consists of the genera Lactococcus and Streptococcus.
Adab, P., Blissett, J., Frew, E., Gill, Paramjit, Griffin, T. L., Griffith, L., Hurley, K. L., Jolly, K., Lancashire, E. R., McGee, E., Pallan, M. J., Parry, J. M., Thompson, J. L.   +12 more
core   +8 more sources

Quenching accumulation of toxic galactose-1-phosphate as a system to select disruption of protein-protein interactions in vivo

BioTechniques, 2004
The reverse two-hybrid system has been developed to readily identify molecules or mutations that can disrupt protein-protein interactions in vivo. This system is generally based on the interaction-dependent activation of a reporter gene, whose product ...
Tea Gunde, Stefan Tanner, Adrian Auf der Maur, Michael Petrascheck, Alcide Barberis   +4 more
doaj   +1 more source

Identification of genes conferring tolerance to lignocellulose-derived inhibitors by functional selections in soil metagenomes [PDF]

, 2016
The production of fuels or chemicals from lignocellulose currently requires thermochemical pretreatment to release fermentable sugars. These harsh conditions also generate numerous small-molecule inhibitors of microbial growth and fermentation, limiting ...
Dantas, Gautam, Ellison, Tyler D, Forsberg, Kevin J, Patel, Sanket, Wang, Bin, Witt, Evan   +5 more
core   +2 more sources

N-terminal chimaeras with signal sequences enhance the functional expression and alter the subcellular localization of heterologous membrane-bound inorganic pyrophosphatases in yeast [PDF]

, 2010
Expression of heterologous multispanning membrane proteins in Saccharomyces cerevisiae is a difficult task. Quite often, the use of multicopy plasmids where the foreign gene is under the control of a strong promoter does not guarantee efficient ...
Drake García, Rocío, Pérez Castiñeira, José Román, Serrano Delgado, Aurelio   +2 more
core   +3 more sources

Galactose inhibition of the constitutive transport of hexoses in Saccharomyces cerevisiae [PDF]

, 2013
The relationship between the pathways of glucose and galactose utilization in Saccharomyces cerevisiae has been studied. Galactose (which is transported and phosphorylated by inducible systems) is a strong inhibitor of the utilization of glucose ...
Catarinella, F. S., Lam, Y. L., Nieman, F. H. M., Toonder, I. M., van der Ham, A. C., van Gent, W. B., Wittens, C. H. A.   +6 more
core   +1 more source

Genome Assembly Revealed MdZAT5 Coordinates Anthocyanin Biosynthesis in Apple Fruit Peel and Flesh by Interacting With MdHY5

Plant Biotechnology Journal, EarlyView.
ABSTRACT Anthocyanins are plant pigments that contribute to fruit coloration and nutritional quality, yet the coordinated regulation of their accumulation in both peel and flesh remains elusive. Here, we present a haplotype‐resolved genome of Malus cv. ‘Royalty’, a model cultivar with consistently red peel and flesh. A zinc‐finger transcription factor,
Mengnan Zhao, Mosen Zhang, Weilei Sun, Shiyao Duan, Jie Zhang, Tingting Song, Yaoxin Wang, Yuncong Yao, Ji Tian   +8 more
wiley   +1 more source

Beyond nocardioform: Transcriptionally active microbes and host responses in equine mucoid placentitis

Equine Veterinary Journal, Volume 58, Issue 2, Page 601-618, March 2026.
Abstract Background Nocardioform placentitis (NP) is an understudied form of equine placentitis historically attributed to nocardioform bacteria, yet it remains uncertain whether these organisms are the sole pathogens involved. Objectives To elucidate the pathophysiology of NP and the host–pathogen interaction. Study Design In vivo clinical multi‐omics
Machteld van Heule, Margo Verstraete, Jamie Kaj Norris, Kinga Barbara Graniczkowsa, Kirsten E. Scoggin, Hossam El‐Sheikh Ali, Barry A. Ball, Ward De Spiegelaere, Peter Daels, Bart C. Weimer, Pouya Dini   +10 more
wiley   +1 more source

Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]

, 2018
FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R., Burrage, Lindsay C., Craigen, William J., Emrick, Lisa, Freeze, Hudson H., Graham, Brett H., Jain, Mahim, Lee, Brendan, Ng, Bobby G., Rosenfeld, Jill A.   +9 more
core   +1 more source

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

Medicinal Research Reviews, Volume 46, Issue 1, Page 238-271, January 2026.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg, Tracie Widjaja, Adriaan P. IJzerman, Daan van der Es   +3 more
wiley   +1 more source

Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics

Molecular Systems Biology, 2015
Elucidating functions of commensal microbial genes in the mammalian gut is challenging because many commensals are recalcitrant to laboratory cultivation and genetic manipulation.
Stephanie J Yaung, Luxue Deng, Ning Li, Jonathan L Braff, George M Church, Lynn Bry, Harris H Wang, Georg K Gerber   +7 more
doaj   +1 more source