Intestinal lipoproteins in the rat with D-(+)-galactosamine hepatitis.
Journal of Lipid Research, 1983 D-(+)-galactosamine (GalN) induces severe reversible hepatocellular injury in the rat accompanied by lecithin: cholesterol acyltransferase (LCAT) deficiency, defective chylomicron (CM) catabolism, and accumulation of abnormal plasma lipoproteins (Lps ...
D D Black, P Tso, S Weidman, S M Sabesin
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Integrating Multiple Analytical Datasets to Compare Metabolite Profiles of Mouse Colonic-Cecal Contents and Feces. [PDF]
, 2015 The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the means by which that microbiome affects the gut. We characterized that phenotype in mice by conducting metabolomic analyses of the colonic-cecal contents ...
Combs, Gerald F +5 more
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Sedative-like effect of intraperitoneal GABA administration in the open field test [PDF]
, 2016 Gamma-Amino Butyric Acid (GABA) is the main inhibitor neurotransmitter of the Central Nervous System (CNS). Its peripheral administration has been matter of discussion. On the one hand, it has been reported that it does not cross the Blood-Brain Barrier (
Gargiulo, Augusto Pascual Ítalo +7 more
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Postępy MikrobiologiiBacteria use a variety of mechanisms in order to successfully survive in hosts. To support proliferation sophisticated means of maintenance in host especially metabolism of carbon and nitrogen is needed. One metabolic mechanism is the metabolism of amino
Petruńko Leon, Gmiter Dawid
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Modular automated solid phase synthesis of dermatan sulfate oligosaccharides [PDF]
, 2014 Dermatan sulfates are glycosaminoglycan polysaccharides that serve a multitude of biological roles as part of the extracellular matrix. Orthogonally protected D-galactosamine and L-iduronic acid building blocks and a photo- cleavable linker are ...
Hahm, Heung Sik +4 more
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Heliyon, 2018 Hepatocellular cellular carcinoma (HCC) is one of the most challenging liver cancer subtypes. Due to lack of cell surface biomarkers and highly metastatic nature, early detection and targeted therapy of HCC is an unmet need.
Shaimaa Yousef +3 more
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Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]
, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
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Endogenous and exogenous glucocorticoids have different roles in modulating endotoxin lethality in D-galactosamine-sensitized mice [PDF]
, 1993 Jesús Corres González +5 more
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Spred2 Deficiency Exacerbates D-Galactosamine/Lipopolysaccharide -induced Acute Liver Injury in Mice via Increased Production of TNFα [PDF]
, 2018 Yang Xu +9 more
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Studies on Gluconeogenesis in Galactosamine Induced Hepatitis
Experimental Biology and Medicine, 1971 SummaryHepatitis was induced in animals treated with D-GalN-HCl (1.5 g/kg) in vitro. Incorporation of alanine-UL-14C, pyruvate-2-14C, and glutamic-3,4-14C acid into glucose by liver slices from GalN-treated animals was found decreased to 20-25% of the control values. The CO2 production from these substrates was impaired by 50%.
D, Monier, S R, Wagle
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