Results 91 to 100 of about 41,097 (233)

Apolipoprotein C-III0 lacks carbohydrate residues: use of mass spectrometry to study apolipoprotein structure.

open access: yesJournal of Lipid Research, 1989
Apolipoprotein C-III (apo C-III) is a 79 amino acid glycoprotein. The sugar moiety of apoC-III is attached to amino acid residue 74 and is thought to consist of 1 mole of galactose, 1 mole of N-acetyl-galactosamine, and either 0, 1, or 2 moles of sialic ...
Y Ito, J L Breslow, B T Chait
doaj   +1 more source

Downregulation of Tumor Necrosis Factor Expression in the Human Mono-Mac-6 Cell Line [PDF]

open access: yes, 1989
Mono-Mac-6 cells, but not U937 cells, can be Induced to rapidly express tumor necrosis factor (TNF) mRNA and protein when triggered with Ilpopolysaccharlde (LPS) at 1 pg/mI. Preincubatlon of the cells for 3 d with low amounts of LPS (10 ng/mI) results In
Blömer, Kathi   +5 more
core   +1 more source

Effects of OK-432 on galactosamine and galactosamine + endotoxin induced fulminant hepatic failure.

open access: yesKanzo, 1985
本研究は,急性肝不全において,溶連菌菌体(OK-432)の網内系賦活による肝不全の予防効果と肝不全進展にエンドトキシン(Et)が重要な役割を果していることを,ガラクトザミン(Gal N) 1.2g/kg及びGal N 0.5g/kg+Et 0.5mg/kg急性肝不全ラットにより明らかにした.すなわち,1) Gal N 1.2g/kg投与ラットはGal N投与72時間以内に,Gal N+EtラットはEt投与6時間以内に全て死亡したが,OK-432 10KEをGal N投与24時間前に投与した群は全て長期生存した.2) OK-432の投与は,Gal N 1.2g/kg投与によるS-GOT, S-GPT,ビリルビンの早期の上昇は抑制しえなかったが,Gal N投与24時間以降の抑制は顕著であった.3 ...
Iwao OIKAWA, Hidetaka EBATA, Michio MITO
openaire   +2 more sources

Intestinal lipoproteins in the rat with D-(+)-galactosamine hepatitis.

open access: yesJournal of Lipid Research, 1983
D-(+)-galactosamine (GalN) induces severe reversible hepatocellular injury in the rat accompanied by lecithin: cholesterol acyltransferase (LCAT) deficiency, defective chylomicron (CM) catabolism, and accumulation of abnormal plasma lipoproteins (Lps ...
D D Black, P Tso, S Weidman, S M Sabesin
doaj   +1 more source

Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation. [PDF]

open access: yes, 1983
We are investigating the hypothesis that carbohydrate-binding molecules on the cell surface are involved in the recirculation of lymphocytes from the bloodstream into lymphoid organs.
Rosen, SD, Stoolman, LM
core   +1 more source

Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]

open access: yes, 1998
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R.   +3 more
core   +1 more source

Xenotransplantation of Human Umbilical Cord Blood Mononuclear Cells to Rats with D-Galactosamine-Induced Hepatitis

open access: yesCell Transplantation, 2008
Cord blood is an attractive cell source in regenerative medicine and represents an alternative to bone marrow. The aim of this study was to investigate whether human umbilical cord blood mononuclear (HUCBM) cells might be valuable in hepatic regenerative
Ana I. Álvarez-Mercado   +8 more
doaj   +1 more source

Interference of the T cell and antigen-presenting cell costimulatory pathway using CTLA4-Ig (abatacept) prevents Staphylococcal enterotoxin B pathology [PDF]

open access: yes, 2017
Staphylococcal enterotoxin B (SEB) is a bacterial superantigen that binds the receptors in the APC/T cell synapse and causes increased proliferation of T cells and a cytokine storm syndrome in vivo.
Carter, Alun J   +10 more
core   +2 more sources

Overview of Aga Genes and their Role in Utilization of N-Acetyl-D-Galactosamine and D-Galactosamine by Bacteria

open access: yesPostępy Mikrobiologii
Bacteria use a variety of mechanisms in order to successfully survive in hosts. To support proliferation sophisticated means of maintenance in host especially metabolism of carbon and nitrogen is needed. One metabolic mechanism is the metabolism of amino
Petruńko Leon, Gmiter Dawid
doaj   +1 more source

Sedative-like effect of intraperitoneal GABA administration in the open field test [PDF]

open access: yes, 2016
Gamma-Amino Butyric Acid (GABA) is the main inhibitor neurotransmitter of the Central Nervous System (CNS). Its peripheral administration has been matter of discussion. On the one hand, it has been reported that it does not cross the Blood-Brain Barrier (
Gargiulo, Augusto Pascual Ítalo   +7 more
core   +1 more source

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