Results 101 to 110 of about 41,097 (233)

Development of asialoglycoprotein receptor directed nanoparticles for selective delivery of curcumin derivative to hepatocellular carcinoma

Heliyon, 2018
Hepatocellular cellular carcinoma (HCC) is one of the most challenging liver cancer subtypes. Due to lack of cell surface biomarkers and highly metastatic nature, early detection and targeted therapy of HCC is an unmet need.
Shaimaa Yousef, Hashem O. Alsaab, Samaresh Sau, Arun K. Iyer   +3 more
doaj   +1 more source

Amelioration of galactosamine-induced nephrotoxicity by a protein isolated from the leaves of the herb, L [PDF]

, 2007
Background Galactosamine (GalN), an established experimental toxin, mainly causes liver injury via the generation of free radicals and depletion of UTP nucleotides. Renal failure is often associated with end stage liver damage.
Mahua Sinha, Prasenjit Manna, Parames C Sil, Z Kmiec, D Keppler, D Keppler, AJ Makin, SK EI-Mofty, P Javle, M Epstein, R Anand, HL Hu, M Mangeney-Andreani, KH Han, K Sugiyama, MA Gyamfi, HK Lim, H Farghali, JS Kang, CK Chauhan, IA Donatus, PS Venkateswaran, DW Unander, M Chatterjee, M Chatterjee, R Bhattacharjee, A Bharani, K Karthikeyan, P Manna, BR Choudhuri, A Ghosh, K Sarkar, A Ghosh, A Ghosh, K Sarkar, K Sarkar, MM Bradford, RW Bonses, CL Crocker, H Esterbauer, M Nishikimi, P Kakkar, J Bonaventura, WH Habig, IK Smith, GL Ellman, PJ Hissin, J Sedlak, A Quintero, O Sire, F Guarner, JD Firth, S Uchida, H Sakamoto, K Moore, SM Khan, PS Oh, SJ Lee, AY Tsoi   +58 more
core   +2 more sources

Immunolocalization of nucleolar proteins after D-galactosamine-induced inhibition of transcription in rat hepatocytes [PDF]

, 1986
No abstract ...
Hadjiolova, Krassimira, Rose, Kathleen M., Scheer, Ulrich   +2 more
core  

Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle [PDF]

, 2017
The paradigm of a cytoplasmic methionine cycle synthesizing/eliminating metabolites that are transported into/out of the nucleus as required has been challenged by detection of significant nuclear levels of several enzymes of this pathway.
Garrido, Francisco, Pajares, María A., Pérez-Miguelsanz, Juliana, Pérez-Sala, Dolores, Reytor, Edel, Vallecillo, Néstor   +5 more
core   +1 more source

Studies on Gluconeogenesis in Galactosamine Induced Hepatitis

Experimental Biology and Medicine, 1971
SummaryHepatitis was induced in animals treated with D-GalN-HCl (1.5 g/kg) in vitro. Incorporation of alanine-UL-14C, pyruvate-2-14C, and glutamic-3,4-14C acid into glucose by liver slices from GalN-treated animals was found decreased to 20-25% of the control values. The CO2 production from these substrates was impaired by 50%.
D, Monier, S R, Wagle
openaire   +2 more sources

Targeted Stimuli-Responsive Dextran Conjugates for Doxorubicin Delivery to Hepatocytes [PDF]

, 2006
A targeted, stimuli-responsive, polymeric drug delivery vehicle has been developed to help alleviate the severe side-effects caused by narrow therapeutic window drugs. Doxorubicin, a commonly used chemotherapeutic agent has been conjugated to dextran by
Joshi, Shilpa M., Tan, Fred E., Ying, Jackie Y., Zaman, Noreen T.   +3 more
core  

Anti-apoptotic and Hepatoprotective Effects of Gomisin A on Fulminant Hepatic Failure Induced by D-Galactosamine and Lipopolysaccharide in Mice

Journal of Pharmacological Sciences, 2008
This study examined the effects of gomisin A, a lignan compound from Schisandra fructus, on D-galactosamine (GalN) and lipopolysaccharide (LPS)-induced hepatic apoptosis and liver failure. Mice were given an intraperitoneal injection of GalN (700 mg/kg) /
Sung-Hwa Kim, Yeong Shik Kim, Sam Sik Kang, KiHwan Bae, Tran Manh Hung, Sun-Mee Lee   +5 more
doaj   +1 more source

Determinación de hexosamines en orina por HPLC para el diagnóstico de mucopolisacariosis tipo III [PDF]

, 2014
Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2014, Tutors: Dra. Elisabet Fuguet Jordà i Dr. Rafael Artuch IriberriIn the present work a reported analytical method was optimized in order to improve the ...
Zamora Campos, Nelson
core  

Mucopoly saccharidosis type maroteaux-lamy, a case report [PDF]

Journal of Mazandaran University of Medical Sciences, 2007
Mucopolysaccharidosis type maroteaux-lamy is a very rare hereditary disease. The disease is marked by the deficiency of the lysosomal enzyme N-Acetyl galactosamine--4-sulfate sulfatase (arylsulfatase B).
A.R. Alaee, F. Rashidi ghader, F. Mojtahedzadeh, A. Tale   +3 more
doaj  

Weiteres über Galactosamin. [PDF]

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1901
Fr. N. Schulz, Fr. Ditthorn.
openaire   +1 more source