Results 141 to 150 of about 356,021 (162)

[Expression and significance of follicular helper T cells and galactose-deficient IgA1 in children with Henoch-Schönlein purpura]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi, 2020
Wang B, Shao-Kuan FR, Dong C.
europepmc   +1 more source

Primary IgA Vasculitis with Nephritis in a Patient with Rheumatoid Arthritis Diagnosed by Anti-galactose-deficient IgA1 Immunostaining. [PDF]

Intern Med, 2019
Karasawa K, Iwabuchi Y, Kyoda M, Akihisa T, Yamaguchi E, Suzuki S, Ogura S, Takabe T, Miyabe Y, Kamiyama T, Nakano M, Manabe S, Kamiyama M, Akiyama K, Sato M, Uchida K, Nitta K, Moriyama T.   +17 more
europepmc   +1 more source

Comprehensive analysis of aberrantly expressed profiles of mRNA and its relationship with serum galactose-deficient IgA1 level in IgA nephropathy. [PDF]

J Transl Med, 2019
Liu Y, Liu X, Jia J, Zheng J, Yan T.
europepmc   +1 more source

The level of galactose-deficient IgA1 in the sera of patients with IgA nephropathy is associated with disease progression [PDF]

Kidney International, 2012
Although high serum levels of galactose-deficient IgA1 (an important biomarker of IgA nephropathy (IgAN)) are found in most patients with IgAN, their relationship to disease severity and progression remains unclear.
Hong Zhang, Krzysztof Kiryluk, Zina Moldoveanu   +2 more
exaly   +5 more sources

Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels [PDF]

Kidney International, 2007
Immunoglobulin A (IgA) nephropathy is the most prevalent form of glomerulonephritis worldwide. A renal biopsy is required for an accurate diagnosis, as no convenient biomarker is currently available.
Robert Wyatt, Zina Moldoveanu, M Tomana
exaly   +6 more sources

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Immunostaining of galactose-deficient IgA1 by KM55 is not specific for immunoglobulin A nephropathy

Clinical Immunology, 2020
Immunoglobulin A nephropathy (IgAN nephropathy, IgAN) is named for the renal pathological features of IgA-dominant immunoglobulin deposition. IgA deposits, however, may also occur in other diseases, from liver disease and inflammation to chronic infections and tumors. Now increasing studies have suggested that galactose-deficient IgA1 (Gd-IgA1) plays a
Hong Liu, Xuejing Zhu, Liang Peng
exaly   +3 more sources

Pathogenic potential of galactose‐deficient IgA1 in IgA nephropathy

Nephrology, 2002
SUMMARY: Recent studies have demonstrated that immune complexes (IC) in the circulation and mesangial deposits in IgA nephropathy (IgAN) patients contain IgA1 molecules deficient in galactose (Gal) in their O‐linked hinge‐region‐associated glycans. Due to this Gal deficiency, terminal N‐acetylgalactosamine (GaINAc) in these side chains is recognized ...
Jiri Mestecky, Jan Novak, Bruce A Julian, Milan Tomana   +3 more
openaire   +1 more source

IgA Nephropathy: Characterization of IgG Antibodies Specific for Galactose-Deficient IgA1

2007
The circulating immune complexes in IgA nephropathy (IgAN) are composed of galactose (Gal)-deficient IgA1 bound to IgG or IgA1 antibodies specific for hinge-region O-linked glycans of Gal-deficient IgA1. To analyze properties of the anti-glycan antibodies, we determined the binding of serum IgG and IgG secreted by Epstein-Barr virus (EBV)- immortalized
Hitoshi, Suzuki, Zina, Moldoveanu, Stacy, Hall, Rhubell, Brown, Bruce A, Julian, Robert J, Wyatt, Milan, Tomana, Yasuhiko, Tomino, Jan, Novak, Jiri, Mestecky   +9 more
openaire   +2 more sources

[Role of IgG antibody to galactose-deficient IgA1 in children with IgA nephropathy].

Zhonghua er ke za zhi = Chinese journal of pediatrics, 2019
Objective: In order to learn the serum level of galactose-deficient IgA1 (GdIgA1), IgG antibody to galactose-deficient IgA1(GdIgA1-IgG) and the clinical role of them in IgA nephropathy(IgAN) children. Method: We compared blood levels of GdIgA1, GdIgA1-IgG in 33 children with IgAN, 38 children with other renal disease (including focal segmental ...
N, Zhou, H, Zhang, X R, Liu, Q, Sun, Q, Meng, Z, Chen, Y, Shen   +6 more
openaire   +1 more source