Results 91 to 100 of about 242,958 (298)
A stochastic model for tumor heterogeneity [PDF]
arXiv, 2015 Phenotype variations define heterogeneity of biological and molecular systems, which play a crucial role in several mechanisms. Heterogeneity has been demonstrated in tumor cells. Here, samples from blood of patients affected from colon tumor were analyzed and fished with a microfluidic assay based on galactose active moieties, and incubated, for ...
arxiv
Advanced Science, EarlyView.A visible‐light‐mediated method has been developed for the direct conversion of biomass into formate at ambient temperature and atmospheric pressure. This approach achieves the selective generation of hydroxyl radicals, which subsequently transform sugars, cellulose, and hemicellulose into formate.
Tong Zhang +7 more
wiley +1 more source
Glucocorticoid-regulated localization of cell surface glycoproteins in rat hepatoma cells is mediated within the Golgi complex. [PDF]
, 1988 Glucocorticoid hormones regulate the post-translational maturation and sorting of cell surface and extracellular mouse mammary tumor virus (MMTV) glycoproteins in M1.54 cells, a stably infected rat hepatoma cell line.
APONTE, Gregory W. +5 more
core +1 more source
An experimental design approach to the chemical characterisation of pectin polysaccharides extracted from Cucumis melo Inodorus [PDF]
, 2014 Extracted pectins have been utilised in a number of applications in both the food and pharmaceutical industries where they are generally used as gelling agents, thickeners and stabilisers, although a number of pectins have been shown to be bioactive ...
Adams +32 more
core +1 more source
Advanced Science, EarlyView.The comprehensive proteomic and N‐glycoproteomic analyses of 45 colorectal cancer tissues with matched normal adjacent tissues identified 7125 intact N‐glycopeptides from 704 glycoproteins. A glycosylation site‐protein function network revealing metabolic dysregulation is constructed and a model differentiating tumors from normal tissues is developed ...
Guobin Liu +10 more
wiley +1 more source
Copper Oxide Nanoparticles Inhibit the Metabolic Activity of \u3cem\u3eSaccharomyces cerevisiae \u3c/em\u3e [PDF]
, 2016 Copper oxide nanoparticles (CuO NPs) are used increasingly in industrial applications and consumer products and thus may pose risk to human and environmental health.
Hallaj, Nadia +3 more
core +1 more source
Advanced Science, EarlyView.The molecular recognition of the sugar moiety of GD3 and Gb3 (globotriaosylceramide) derivatives by Siglec‐7 has been thoroughly studied offering insights for cancer diagnostics and therapies. A combination of structural biology techniques, nuclear magnetic resonance (NMR) spectroscopy, physicochemical analysis, and in silico methods suggested that ...
Cristina Di Carluccio +15 more
wiley +1 more source
Advanced Science, EarlyView.Enzymatic introduction of azido‐sialic acid residues to the glycans on exosomes enables a new and efficient approach for exosomal functionalization with various probes, including biotin and fluorophores, by biocompatible click chemistry, thereby facilitating detailed investigations of exosomes, such as their glycan profiles, cellular uptake, etc., and ...
Sayan Kundu +5 more
wiley +1 more source
Tel1ATM dictates the replication timing of short yeast telomeres [PDF]
, 2014 Telomerase action is temporally linked to DNA replication. Although yeast telomeres are normally late replicating, telomere shortening leads to early firing of subtelomeric DNA replication origins.
Alessandro Bianchi +4 more
core +2 more sources
Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species
Advanced Science, EarlyView.This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu +15 more
wiley +1 more source