Results 91 to 100 of about 168,620 (305)
, 2009 We describe the synthesis of mimetics of the a23 and a26 sialogalactoside substrates of influenza neuraminidase which include the oseltamivir pharmacophore, and report the sub-nanomolar affinities for these novel neuraminidase inhibitors.
Stephen R Martin (8117216) +4 more
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Animal Models and Experimental Medicine, EarlyView.At the genomic level, a large number of differentially expressed genes (DEGs) and aging‐related DEGs have been screened. Ten hub genes, such as IFNγ and IRF7, have been identified and shown potential value in the diagnosis of PD, holding promise as novel biomarkers to facilitate early and precise diagnosis.
Haojie Wu +3 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.ErZhi formula (EZF) is composed of Ligustri Lucidi Fructus (LLF) and Ecliptae herba (EH). Ovariectomized (OVX) and sham rats received 12‐week intragastric treatment with EZF, alendronate, and vehicle saline. Gastrocnemius tissues were harvested to systematically evaluate pharmacodynamic changes in skeletal muscle morphology, mitochondrial ...
Yuqing Pang +7 more
wiley +1 more source
Síntese e caracterização de um novo complexo modelo para sítio ativo de metaloenzimas de cobre [PDF]
, 2006 TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Metais de transição fazem parte do sítio ativo de diversas metaloenzimas que desempenham papéis fundamentais em sistemas vivos.
CAMARGO, Tiago Pacheco de
core
Influence of galactose cataract on erythrocytic and lenticular glutathione metabolism in albino rats
Indian Journal of Ophthalmology, 2011 Context: Glutathione depletion has been postulated to be the prime reason for galactose cataract. The current research seeks the prospect of targeting erythrocytes to pursue the lens metabolism by studying the glutathione system.
M Jyothi, R Sanil, S Shashidhar
doaj +1 more source
Targeting CYP450 modulation to decrease the risk of induced cataract in the experimental model
Indian Journal of Ophthalmology, 2010 Background: Diabetes is one of the major causes of cataract. Some drugs prescribed for the treatment of diabetes are the modulators of CYP450, which may alter the risk of cataract.
Patel D +4 more
doaj
, 2019 Our previous research showed that CD38 played vital roles in Ang-II induced hypertrophy and high fat diet induced heart injury. However, the role of CD38 in heart aging is still unknown. In the present study, we reported that CD38 knockdown significantly
Hong-Bo Xin (7059) +10 more
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, 2021 © 2021 Elsevier B.V.A highly sensitive lectin-based impedimetric detection method has been developed for the determination of galactose in human serum samples.
Daeho Jeong, Won-Yong Lee
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, 2008 Succinic acid-producing Anaerobiospirillum succiniciproducens was anaerobically grown on galactose, galactose/glucose, or galactose/lactose in order to study its galactose fermentation. Unlike a previous report, A.
Chang, Ho Nam, Lee, PC, Lee, SangYup
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