Results 121 to 130 of about 242,958 (298)

Synthesis of (‐)‐8a epi‐Lentiginosine via Tsuji‐Trost Reaction of d‐Glucose‐Derived Allylic Alcohols and Crystal Structure Analysis

open access: yesAsian Journal of Organic Chemistry, Accepted Article.
An indolizidine alkaloid, (‐)‐8a‐epi‐lentiginosine was synthesized from d‐glucose using the Pd‐BiPhePhos catalyzed intramolecular Tsuji‐Trost reaction of non‐derivatized allylic alcohol as a key construction of the hydroxylated pyrrolidine ring to give the desired product in good yield and high diasterespecificity stereospecificity (dr = 97:3).
Sunisa Akkarasamiyo   +3 more
wiley   +1 more source

Immobilization of Kluyveromyces lactis β‐Galactosidase on Meso‐macroporous Silica: Use of Infrared Spectroscopy to Rationalize the Catalytic Efficiency

open access: yesChemPlusChem, Volume 87, Issue 12, December 2022., 2022
A deeper understanding regarding the enzyme‐carrier interactions and the enzyme conformation may bring clues about the inherent processes that occur during enzyme immobilization. In this study, the enzyme β‐galactosidase was immobilized on a meso‐macroporous silica carrier, and infrared spectroscopy allowed the search for such clues to explain the ...
Diogo Videira‐Quintela   +3 more
wiley   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam   +13 more
wiley   +1 more source

Purification and properties of a plant Agglutinin [PDF]

open access: yes, 1958
Thesis (M.A.)--Boston UniversityThis study involved work with extracts of the seeds of Bauhinia purpurea alba, in which an N specific lectin was found by Mäkelä (37) and Boyd and McMaster (16). There were two main purposes in mind.
Everhart, Donald Lee
core   +1 more source

Sugar‐sensing swodkoreceptors and swodkocrine signaling

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley   +1 more source

Cinética de inibição por galactose e glicose na hidrólise de lactose por b-galactosidase em massa de células permeabilizadas de Kluyveromyces lactis

open access: yesRevista do Instituto de Latícinios Cândido Tostes, 2008
O efeito de diferentes concentrações de galactose, glicose e de mistura de galactose e glicose na cinética de hidrólise de lactose por b-galactosidase utilizando células permeabilizadas de Kluyveromyces lactis como biocatalisador foi realizado.
Edimar A . F. Fontes   +3 more
doaj  

Genetically enhanced recombinant lectins for glyco-selective analysis and purification [PDF]

open access: yes, 2011
- Generation of a library of recombinant prokaryotic lectins (RPL’s) through random mutagenesis of the carbohydrate binding sites of bacterial lectins. - Characterisation of mutant lectins with respect to structure and specificity - Provision of mutant
Clarke, Paul A.   +5 more
core  

Antigen targeting to dendritic cells: Still a place in future immunotherapy?

open access: yesEuropean Journal of Immunology, Volume 52, Issue 12, Page 1909-1924, December 2022., 2022
Dendritic cell‐based immunotherapy is a promising vaccination strategy to treat infectious diseases, autoimmunity, and cancer. In this review, we present an overview on the current state of antigen targeting approaches via C‐type lectin receptors, with an outlook on future developments and potential for clinical translation.
Patrizia Stoitzner   +4 more
wiley   +1 more source

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