Results 121 to 130 of about 261,281 (306)

The Skn7 Response Regulator of \u3ci\u3eSaccharomyces cerevisiae\u3c/i\u3e Interacts with Hsf1 In Vivo and Is Required for the Induction of Heat Shock Genes by Oxidative Stress [PDF]

, 2000
The Skn7 response regulator has previously been shown to play a role in the induction of stress-responsive genes in yeast, e.g., in the induction of the thioredoxin gene in response to hydrogen peroxide.
Erkine, Alexander M., Gross, David S., Johnson, Anthony L., Johnston, Leland H., Makino, Kozo, Morgan, Brian, Raitt, Desmond C.   +6 more
core   +1 more source

Engineered B7‐H3 Binding in Modular Gp2 Miniproteins

Biotechnology and Bioengineering, EarlyView.
ABSTRACT B7‐H3, an important immune checkpoint modulator of T‐cell function, is a tumor vasculature biomarker and is overexpressed in a variety of cancers. Its expression is associated with tumor growth, metastasis, and poor clinical prognosis, which makes B7‐H3 an appealing target for diagnostics and therapeutics.
Abbigael Harthorn, Hannah K. Windsor, Zachary Schmitz, Nathaniel Cheung, Ebube Agwaramgbo, Benjamin J. Hackel   +5 more
wiley   +1 more source

Validade e análise de sensibilidade dos coeficientes cinéticos do modelo matemático mecanístico proposto para predizer a cinética de hidrólise de lactose por β-galactosidase de células permeabilizadas de kluyveromyces lactis

Revista do Instituto de Latícinios Cândido Tostes, 2008
Um modelo matemático mecanístico foi desenvolvido para descrever a hidrólise de lactose, levando em consideração o efeito de inibição por galactose. Foi utilizado um sistema dinâmico de equações diferenciais ordinárias da variação de lactose, glicose e ...
Edimar A . F. Fontes, Flávia M. L. Passos, Frederico J. V. Passos, Paulo Rogério Fontes   +3 more
doaj  

AuNP-Agglomerated monoliths in pipette tips for lectin affinity extraction of glycoproteins [PDF]

, 2010
• To in situ fabricate ethylene dimethacrylate porous polymer monoliths within the confines of a commercial 20 μL polypropylene pipette tips. • To enhance the monolith surface area by immobilising AuNPs and then functionalise the AuNPs with ECL lectin
Alwael, Hassan, Connolly, Damian, O'Connor, Brendan, Paull, Brett, Thompson, Roisin, Twamley, Brendan   +5 more
core  

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Does p‐lactate increase in patients with GSD1 after ingesting a meal with common‐size sources of fructose and galactose? Observations from a prospective, non‐blinded, crossover pilot study

JIMD Reports
Ingestion of fructose and galactose may result in elevated lactate concentrations in patients with glycogen storage disease type 1 (GSD1). In this randomized cross‐over pilot study, 7 patients with GSD 1a (6) and GSD1b (1) orally consumed a common‐size ...
Camilla Diana B. Caroee, Allan M. Lund
doaj   +1 more source

Real time in vivo efficacy monitoring of desialylation and perforation enhanced immunotherapy of cancer

BMEMat, EarlyView.
A multifunctional nanomedicine is designed to engineer NK cells for enhanced cancer immunotherapy through perforation and desialylation, enabling real‐time monitoring of ATP and GrB levels for precise efficacy assessment. Abstract Efficient enhanced NK cell therapy is of critical importance in the immune treatment of cancer.
Yuanjiao Yang, Yuru Wang, Xuemei Li, Chaoyi Yang, Yuhui Yang, Yanyun Fang, Lin Ding, Yunlong Chen, Huangxian Ju   +8 more
wiley   +1 more source

Cinética de inibição por galactose e glicose na hidrólise de lactose por b-galactosidase em massa de células permeabilizadas de Kluyveromyces lactis

Revista do Instituto de Latícinios Cândido Tostes, 2008
O efeito de diferentes concentrações de galactose, glicose e de mistura de galactose e glicose na cinética de hidrólise de lactose por b-galactosidase utilizando células permeabilizadas de Kluyveromyces lactis como biocatalisador foi realizado.
Edimar A . F. Fontes, Flávia M. L. Passos, Frederico J. V. Passos, Paulo Rogério Fontes   +3 more
doaj  

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Topical aspirin provides protection against galactosemic cataract

Indian Journal of Ophthalmology, 1997
Effect of twice daily administration of aspirin eyedrops on the onset and progression of cataract induced by 30% galactose diet was studied. On the 30th day of galactose feeding while all control group rats showed complete stage IV opacity, those ...
Gupta Suresh, Joshi Sujata, Tandon Radhika, Mathur Priya   +3 more
doaj