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Galactose-α-1,3-galactose syndrome: an Italian survey [PDF]

open access: possibleEuropean Annals of Allergy and Clinical Immunology, 2017
Background. The term of α-Gal syndrome, which includes the delayed allergy to red meat and the allergic reactions following the administration of cetuximab, is associated to the presence of specific IgE to α-Gal. In Italy, only anecdotal cases were reported so far.
D, Villalta   +12 more
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Perinatal galactose metabolism

The Journal of Pediatrics, 1985
Galactose is a major nutrient in normal newborn infants and serves as a substrate for energy production and fuel storage and a regulator of carbohydrate assimilation. Inborn errors of galactose metabolism have contributed to our understanding of the potential toxicity of this carbohydrate.
R M, Kliegman, J W, Sparks
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Glucose-galactose malabsorption

The Journal of Pediatrics, 1966
This is the first report in the American literature of a patient with a deficiency of gastrointestinal absorption of glucose and galactose. The disease is characterized by severe, chronic, watery diarrhea starting soon after birth. Marked improvement occurs following the substitution of the offending sugars by fructose.
J F, Marks, J B, Norton, J S, Fordtran
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Galactose oxidase

2002
The free radical-coupled copper catalytic motif has emerged as the unifying feature of a new family of enzymes, the radical copper oxidases. Their highly evolved active sites include a novel amino acid modification, the Tyr-Cys dimer, that forms spontaneously through self-processing of the protein during its maturation. The active site is remarkable in
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HEREDITARY GALACTOSE DISEASE

Journal of the American Medical Association, 1958
Galactosemia and galactosuria characterize a hereditary disease caused by an inborn error of metabolism, which produces in an affected child the inability to metabolize galactose and lactose normally. Some appropriate terms that have been suggested and used synonymously are galactose diabetes, essential galactosuria, congenital galactosemia, congenital
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Endogenous galactose formation in galactose-1-phosphate uridyltransferase deficiency

Archives of Physiology and Biochemistry, 2014
Patients with classical galactosaemia (galactose-1-phosphate uridyltransferase (GALT) deficiency) manifest clinical complications despite strict dietary galactose restriction. Therefore the significance of endogenous galactose production has been assessed.
Peter, Schadewaldt   +4 more
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Galactose toxicity in the chick: Oxidation of radioactive galactose

Biochimica et Biophysica Acta (BBA) - General Subjects, 1970
Abstract Radioactive galactose has been shown to be converted to 14 CO 2 by both the intact chick and by various tissues in vitro . The pattern of 14 CO 2 liberation by the intact chick was not related to the sex of the chick nor to whether the 14 C was in C-1 or C-2 position. [1- 14 C]Glucose was metabolized to 14 CO 2 at a faster rate than [
H J, Wells, M, Gordon, S, Segal
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GALACTOSE STUDIES IN AN INFANT WITH IDIOPATHIC GALACTOSE INTOLERANCE

Pediatrics, 1948
Galactose metabolism has been studied in a group of convalescent children and in one patient with galactosuria, hepatomegaly and splenomegaly, and cataracts. The galactose tolerance of the convalescent infants studied following intravenous injection of the sugar was similar to that observed in healthy adults.
L, GREENMAN, J C, RATHBUN
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