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Galactose disorders: An overview
Journal of Inherited Metabolic Disease, 1990SummaryThere are three separate disorders of galactose metabolism of clinical importance. Galactokinase deficiency mainly causes cataracts which regress without complications providing a galactose‐free diet is started early enough. UDPgalactose‐4‐epimerase deficiency seems extremely rare.
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Galactose-I-Phosphoric Acid in Galactose Metabolism
Nature, 1939The synthesis of α (?)-galactose-l-phosphoric acid has provided a means of examining the constitution of the galactosephosphate accumulating in the liver during galactose assimilation1. Both natural and synthetic esters are non-reducing, very readily hydrolysed by acid, and resistant to alkaline hydrolysis.
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Galactose-sensitive mutants of Salmonella I. Metabolism of galactose
Biochimica et Biophysica Acta, 1961Abstract The metabolism of galactose was studied in peculiar mutants of Salmonella (M mutants) which (1) fail to produce acid from galactose and (2) undergo severe bacteriolysis when grown in the presence of galactose. The mutants were shown to have a specific hereditary defect in the enzyme UDPGal-4-epimerase, and to accumulate intracellularly ...
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Galactose 1-phosphate in galactose cataract
Biochimica et Biophysica Acta, 1955Y, SCHWARZ, L, GOLBERG
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