Results 131 to 140 of about 19,566 (289)
Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children
British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2028-2048, July 2026.This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits +8 morewiley +1 more sourceConcomitant 5‐Aminosalicylic Acid Does Not Affect the Efficacy of Janus Kinase Inhibitors in Ulcerative Colitis
Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 109-113, July 2026.We evaluated whether concomitant 5‐aminosalicylic acid (5‐ASA) influences clinical remission in patients with ulcerative colitis (UC) receiving Janus kinase inhibitors (JAKi). In this retrospective, multicenter cohort study, UC patients receiving tofacitinib (n = 181), upadacitinib (n = 313), or filgotinib (n = 139) were included.Antonio Tursi, Andrea Pasta, Walter Elisei, Brigida Barberio, Giammarco Mocci, Giovanni Maconi, Antonietta Gerarda Gravina, Raffaele Pellegrino, Giorgia Bodini, Edoardo Vincenzo Savarino, Alfredo Papa, Italian Network for Inflammatory Bowel Diseases (IN‐IBD), Davide G. Ribaldone, Antonio Ferronato, Greta Lorenzon, Davide Checchin, Francesca Lambroglia, Francesco Ferrara, Carla Felice, Giovanni Cataletti, Giorgia Bodini, Andrea Pasta, Giovanni Aragona, Patrizia Perazzo, Federica Gaiani, Stefano Kayali, Fabio Cortellini, Francesco Costa, Lorenzo Bertani, Antonella Scarcelli, Mariaelena Serio, Emanuele Bendia, Laura Bolognini, Daniele Balducci, Claudia Quatraccioni, Francesco Martini, Michele Montori, Simona Piergallini, Francesca Maria Onidi, Paolo Usai Satta, Giorgia Orrù, Raffaele Colucci, Francesco Bachetti, Gabrio Bassotti, Elisabetta Antonelli, Costantino Zampaletta, Giulia Rocco, Carlotta Sacchi, Franco Scaldaferri, Daniele Napolitano, Roberto Faggiani, Michela Di Fonzo, Rita Monterubbianesi, Cristiano Pagnini, Maria Giovanna Graziani, Maria Carla Di Paolo, Roberta Pica, Maddalena Zippi, Andrea Cocco, Claudio Cassieri, Roberto Lorenzetti, Gian Marco Giorgetti, Valeria Clemente, Patrizio Scarozza, Girolamo Bevevino, Giulia Zerboni, Federico Iacopini, Giacomo Forti, Laurino Grossi, Serafina Fiorella, Giovanni Lombardi, Marta Patturelli, Giuliana Vespere, Silvia Sedda, Vittorio D’Onofrio, Leonardo De Luca, Caterina Mucherino, Elvira D’Antonio, Laura Montesano, Pietro Capone, Guido Daniele Villani, Antonio Cuomo, Laura Donnarumma, Nicola Della Valle, Giuseppe Pranzo, Paolo Tonti, Viviana Neve, Libera Fanigliulo, Leonardo Allegretta, Alessia Immacolata Cazzato, Stefano Scorza, Manuela Marzo, Ileana Luppino, Francesco Luzza, Rocco Spagnuolo, Stefano Rodinò, Ladislava Sebkova, Antonio De Medici, Domenico Catarella, Dario D’Agostino, Elisabetta Di Bartolo +100 morewiley +1 more sourceSeals of the Galapagos Islands
, 1984 The Galapagos archipelago has been colonized by two species of otariid, the fur seal, Arctocephalus galapagoensis, and the sea lion, Zalophus californianus wollebaeki. The former probably arrived from South America and the latter from North America, both Bonner, W. Nigelcore +1 more sourceUndetection of vector-borne viruses in equids of Galapagos Islands
Frontiers in Veterinary ScienceDomestic species, including equids, were introduced in the Galapagos Islands in the XIX century. Equine vector-borne diseases are circulating in South America but their occurrence in the Galapagos Island was unknown.Gina Zanella, Cécile Beck, José-Carlos Valle-Casuso, José-Carlos Valle-Casuso, Madeline Anthony, Madeline Anthony, Marilyn Cruz, Alberto Vélez, Rommel Lenin Vinueza, Gaëlle Gonzalez +9 moredoaj +1 more sourceEffects of Transcutaneous Electrical Nerve Stimulation, Electrical Muscle Stimulation, Exercise and Heat on Back Pain—A Randomized Controlled Clinical Exploratory Trial
European Journal of Pain, Volume 30, Issue 6, July 2026.ABSTRACT Background
This randomized controlled study compared different forms of therapy for chronic back pain. Methods
Seventy‐nine patients with chronic back pain with a duration of symptoms of more than 6 months were included in the study and randomly assigned to one of four therapy groups (a) sports therapy with a focus on strength training (SG ...Thorsten Schmidt, Sonja Kossiski, Hanna Kornprobst, Laura von Levern, Dominik M. Schulte, Manon Sendel, Ralf Baron, Janne Gierthmühlen +7 morewiley +1 more sourceAdaptation of the International Consortium for Health Outcomes Measurement Standard Set for Inflammatory Bowel Disease for Routine Collection in Clinical Practice
JCC Plus, Volume 1, Issue 4, July 2026.ABSTRACT Background and Aims
Value‐based healthcare (VBHC) is based on evaluating clinical interventions according to their ability to improve outcomes and costs to finally enhance quality of care. As part of an initiative to introduce VBHC in inflammatory bowel disease (IBD), our project aimed to adapt the International Consortium for Health Outcomes ...Xavier Calvet, Iago Rodríguez‐Lago, Jose‐Lázaro Pérez‐Calle, Hugo Bronchalo‐Bautista, Elena Barbazán‐García, on behalf of the EEImprove Collaborative Project TEam, Alberto Vegas‐Miguel, Alicia Diaz‐Redondo, Ane Fullaondo‐Zabala, Carles Illa, Celia Albaladejo Blanco, Daniel Ceballos, Ignacio Marín‐Jiménez, Jesus Barrio Andres, Jesús Gonzalo Gómez Gómez, Jone Ortiz de Zaarate Sagastagoitia, Juan Manuel Sánchez Lledó, Laura Gómez‐Irwin, Luis Alberto Menchen Viso, Maite Zabala Ugarteburu, María Carme Nicolás Herrerías, María Dolores Martín‐Arranza, María Esteve Comas, María Mercedes Ortiz Otero, Mirari San Felix Carrasco, Mónica Sierra‐Ausin, Monsterrat Aceituno Quintanilla, Olga Merino Ochoa, Pilar López Serrano, Raúl Martín Puentes, San José Fernando Bermejo, Susana Castelo Zas, Susana Lorenzo Martínez, Yamile Zabana +33 morewiley +1 more sourceTrends in Corticosteroid Use and Excess in Patients With Inflammatory Bowel Disease in the United States, Sweden, and Denmark
JCC Plus, Volume 1, Issue 4, July 2026.ABSTRACT Background and Aims
Studies show that corticosteroid use in inflammatory bowel disease (IBD) exceeds guideline recommendations. To better understand patterns of corticosteroid use and identify factors associated with excess exposure, we examined long‐term trends in corticosteroid prescribing practices in large IBD populations across 3 ...Tim Raine, Gil Y. Melmed, J. Casey Chapman, Bobby Lo, Jonas Söderling, Laura E. Targownik, Nidhi Shukla, Si Xuan, Elena Marced Barrachina, Dolly Sharma, Johan Burisch, Ola Olén +11 morewiley +1 more source