Results 131 to 140 of about 50,260 (281)

Development of CAR NK Cell Lines Selectively Targeting Cancer Cells Expressing Membrane Hsp70

open access: yesMedComm, Volume 7, Issue 5, May 2026.
This work presents a novel CAR NK cell platform targeting membrane‐bound Hsp70, a tumor‐specific antigen broadly expressed on solid tumors but not on normal cells. Computational modeling confirmed strong binding between the CAR construct and the Hsp70‐derived TKD peptide.
Khouloud Hachani   +17 more
wiley   +1 more source

Effect of Mirikizumab on Clinical and Endoscopic Outcomes Based on Prior Advanced Therapy Failure in Patients With Moderately to Severely Active Ulcerative Colitis

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 4, May 2026.
ABSTRACT Background Mirikizumab demonstrated efficacy in moderately‐to‐severely active ulcerative colitis, including in patients with prior advanced therapy failure (PATF) (Phase 3: LUCENT‐1 [NCT03518086], LUCENT‐2 [NCT03524092]). This post hoc analysis evaluates mirikizumab efficacy by number/mechanism of PATF.
Ailsa Hart   +15 more
wiley   +1 more source

Haematology and biochemistry reference intervals of Galapagos short-eared owls (<i>Asio flammeus galapagoensis</i>) from Floreana Island. [PDF]

open access: yesConserv Physiol
Vaasjo E   +7 more
europepmc   +1 more source

Galapagos - A virtual scientific field study for independent learners [PDF]

open access: yes, 1997
Balbirnie, C.   +3 more
core  

Real‐World Effectiveness and Safety of Upadacitinib in Crohn's Disease: Insights From the Eneida Registry

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 4, May 2026.
ABSTRACT Background Upadacitinib (UPA) is the first oral Janus kinase (JAK) inhibitor approved for the treatment of Crohn's disease (CD). Real‐world data, particularly from large nationwide cohorts, remain limited. This study aimed to evaluate the real‐world effectiveness, safety, and treatment persistence of UPA in patients with CD.
M. Iborra   +51 more
wiley   +1 more source

Into the Darkness: Unveiling Unexpected Records of the Nonnative Millipede Prosopodesmus jacobsoni Silvestri, 1910 (Polydesmida: Haplodesmidae) in Brazilian Caves

open access: yesAustral Entomology, Volume 65, Issue 2, May 2026.
ABSTRACT This study expands the known distribution of the nonnative millipede Prosopodesmus jacobsoni in Brazil and reports its presence in cave environments for the first time in the country. Based on recently collected material and historical records, the species is shown to maintain stable populations in subterranean systems in the states of ...
Juan Romero‐Rincon   +3 more
wiley   +1 more source

High-quality de novo genome assembly for the Galápagos endemic lava gull using Oxford Nanopore Technologies. [PDF]

open access: yesG3 (Bethesda)
Martin JA   +7 more
europepmc   +1 more source

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