Results 191 to 200 of about 19,566 (289)

Cost‐Effectiveness of Venetoclax‐Based Treatment in Treatment‐Naïve Fit Patients With CLL Without TP53 Aberrations

European Journal of Haematology, Volume 116, Issue 6, Page 873-882, June 2026.
ABSTRACT The GAIA‐CLL13 trial showed that venetoclax‐obinutuzumab (Ven‐O) based regimens, with or without ibrutinib, offer superior efficacy compared to chemoimmunotherapy (CIT) with regards to progression free survival (PFS) in fit, treatment‐naïve (TN) CLL patients. However, their higher costs warrant a cost‐effectiveness evaluation.
Lars Holger Ehlers, Mark‐David Levin, Marjolein van der Klift, Morten Berg Jensen, Hoa Thi Tuyet Tran, Arnon P. Kater, Carsten Utoft Niemann   +6 more
wiley   +1 more source

Fcγ-receptor-activation by circulating immune complexes in systemic autoimmune diseases and its reduction by CD19-CAR T cell therapy. [PDF]

Rheumatology (Oxford)
Freitag M, Kolb P, Falcone V, Claus M, Schröder P, Andreeva I, Rodon L, Ewald M, Deicher FS, Stütz AN, Distler JHW, Blank N, Grieshaber-Bouyer R, Muñoz LE, Lorenz HM, Schett G, Merkt W.   +16 more
europepmc   +1 more source

Speciation History Shapes Patterns of Assemblage Species Richness in Birds

Ecology Letters, Volume 29, Issue 6, June 2026.
Speciation is the ultimate source of biodiversity. However, because most species arise in spatial isolation, how speciation shapes patterns of co‐occurring species richness remains unclear. Here we examine how the legacy of speciation affects contemporary biodiversity patterns via a phylogenetic model and show that this build‐up is remarkably slow and ...
Bouwe R. Reijenga, Rampal S. Etienne, David J. Murrell, Alex L. Pigot   +3 more
wiley   +1 more source

Transcriptomic detection of Candidatus Allocryptoplasma (Anaplasmataceae) in Galápagos marine iguanas (Amblyrhynchus cristatus, Iguanidae). [PDF]

Parasit Vectors
Uesseler F, Werner L, Schaffer S, Ibáñez A, Glaberman S, Páez-Rosas D, Guayasamin JM, Hofreiter M, Steinfartz S, Franke-Gerth FA.   +9 more
europepmc   +1 more source

The Evolution of Hutchinsonian Climatic Niche Hypervolumes in Gymnosperms

Global Ecology and Biogeography, Volume 35, Issue 6, June 2026.
ABSTRACT Aim The niche is a fundamental concept in theoretical and experimental ecology and is used to describe a wide range of ecological processes from species' interactions with the environment to community assemblies. A common way to represent the niche is through a multidimensional geometry known as the Hutchinsonian niche hypervolume.
Fernanda S. Caron, Jānis Lazovskis, David F. R. P. Burslem, Juliano Morimoto   +3 more
wiley   +1 more source

Human Infection by Zoonotic Eye Fluke Philophthalmus lacrymosus, South America. [PDF]

Emerg Infect Dis
Weitzel T, Cordero EM, Mujica T, Aravena C, Phillips BE, Yabsley MJ, Lewbart GA, Páez-Rosas D, Jercic MI, Capasso S.   +9 more
europepmc   +1 more source

Inequities in inflammatory bowel disease care: a Tasmanian case study with proposed solutions

Internal Medicine Journal, Volume 56, Issue 6, Page 949-957, June 2026.
Abstract There is well‐recognised inequity of care for people treated with inflammatory bowel disease (IBD) between metropolitan and regional areas. We aim to describe these barriers to care using Tasmania as a case example and to suggest solutions for addressing these barriers that can be used in Tasmania and beyond.
Alexander T Elford, Alyssa Pettersen, Emily Woods, Linda Boxhall, Zachiary Cooke, Anna Prebble, Jennifer Shoobridge, Jarrad Wilson, Scott Fanning   +8 more
wiley   +1 more source

Genomic and biogeographic patterns of endemic geckos in the Galapagos Islands reveal population structure and species delimitation on inhabited islands. [PDF]

Sci Rep
Pozo G, Guadalupe JJ, Pozo MJ, Cisneros-Heredia DF, Cerca J, Alarcón-Bolaños P, Suárez MV, Dávila-Játiva M, Peñaherrera-Romero E, Brito-Zapata D, Velasco-Cedeño D, Torres ML.   +11 more
europepmc   +1 more source

French guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 6, Page 963-979, June 2026.
New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.
Marie Masson Regnault, Emilie Brenaut, Marie‐Emeline Marniquet, Carla Berthault, Lea Canoen, Clarisse Marcombes, Audrey Melin, Raphaël Ouakrat, Julie Charles, Stephane Mouret, Olivier Potie, Laetitia Penso, Laura Pina Vegas, Guillaume Larid, Marine Roux, Colombe Bougeard, Sandy Sylvain, Clara Labonne, Tania Randriamiarana, Da Hee Pitaud, Floriane Etheve, Jeremy Gottlieb, Laurie Gouillon, Marine Chastagner, Emilie Sbidian, Hélène Aubert, on behalf of the Psoriasis Research Group of the French Society of Dermatology (Groupe de Recherche sur le Psoriasis de la Société Française de Dermatologie), Hélène Aubert, Marie Masson Regnault, Emilie Brenaut, Emilie Sbidian, Laura Pina Vegas, Laetitia Penso, Jeremy Gottlieb, Marine Roux, Clara Labonne, Tania Randriamiarana, Floriane Etheve, Da Hee Pitaud, Marie‐Emeline Marniquet, Carla Berthault, Clarisse Marcombes, Audrey Melin, Colombe Bougeard, Julie Charles, Olivier Potie, Léa Canoen, Laurie Gouillon, Marine Chastagner, Sandy Sylvain, Guillaume Larid, Raphaël Ouakrat   +51 more
wiley   +1 more source

Safety and Efficacy of Ozanimod in Patients With Moderately to Severely Active Ulcerative Colitis Stratified by Age. [PDF]

Inflamm Bowel Dis
Faye AS, Rubin DT, Siegel CA, Long MD, Khan N, Danese S, Irving PM, Cross RK, Blumenstein I, Armuzzi A, Horst SN, Dignass A, Kobayashi T, Lawlor G, Krakovich A, Petersen A, Liu Z, Wang D, Jain A, Ananthakrishnan AN, Sabino J.   +20 more
europepmc   +1 more source