Results 1 to 10 of about 520 (135)

Microfluidic Engineering of Chitosan‐Coated Nanoemulsions for Controlled Release and Stability in Space Pharmaceutics

Advanced Materials Technologies, EarlyView.
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale, Nguyen Van Duc Long, Philip M Williams, Volker Hessel   +3 more
wiley   +1 more source

Multi‐Dielectric Metasurfaces for Ultrabright, Tunable Structural Color and Reconfigurable Optical Filtering with Extraordinarily Large Color Span

Advanced Optical Materials, EarlyView.
Structural color generation is an emerging field for digital display and printing applications. This report presents a novel truncated‐cone design and the first use of GaP sandwiched between two layers of TiO2, demonstrating ultra‐bright, tunable colors with a record color gamut.
Md Rumon Miah, Yavuz Selim Aydın, Hilmi Volkan Demir   +2 more
wiley   +1 more source

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

Advanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino, Phuoc Thien Phan, James Davies, Bibhu Sharma, Tianruo Guo, Chi Cong Nguyen, Nigel H. Lovell, Thanh Nho Do   +7 more
wiley   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

Effectiveness of Virtual Reality for Pain Relief in Procedures Related to Obstetrics and Gynaecology: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Immersive virtual reality (VR) technology offers a non‐invasive, non‐pharmacological approach to reduce pain perception in patients undergoing diagnostic or interventional procedures. Objective To systematically evaluate the efficacy of immersive VR technology in reducing pain perception during obstetric and gynaecological ...
Jhia Jiat Teh, Filipa Campos, Adam Koczoski, Trisha Valencia, Michael P. Rimmer, Bassel H. Al Wattar   +5 more
wiley   +1 more source

PanGraphRNA: An efficient and flexible bioinformatics platform for graph pangenome‐based RNA‐seq data analysis

Journal of Integrative Plant Biology, EarlyView.
PanGraphRNA is an easy‐to‐use platform that improves RNA‐seq analysis by using graph pangenomes instead of a single reference genome. It increases read alignment accuracy, detects important genes missed by traditional methods, and works across major crops, helping researchers obtain more reliable transcriptome results for diverse plant research and ...
Yifan Bu, Zhixu Qiu, Wen Sun, Yishui Han, Yifan Liu, Jing Yang, Minggui Song, Zenglin Li, Songyu Liu, Yuzhou Zhang, Chuang Ma   +10 more
wiley   +1 more source

Noble gases and nitrogen in material from asteroid Bennu

Meteoritics &Planetary Science, EarlyView.
Abstract We report the elemental and isotopic abundances of all stable noble gases (helium, neon, argon, krypton, and xenon) in eight particles from asteroid Bennu returned by NASA's OSIRIS‐REx mission. We also report nitrogen abundances and isotopic ratios that were analyzed alongside neon and argon in four additional Bennu particles.
B. Marty, L. Zimmermann, E. Füri, D. V. Bekaert, J. J. Barnes, A. N. Nguyen, H. C. Connolly, D. S. Lauretta   +7 more
wiley   +1 more source

Ryugu Reference Project: Recommendations from the Measurement Definition Team

Meteoritics &Planetary Science, EarlyView.
Abstract Sample return missions play a significant role in planetary science by providing pristine extraterrestrial materials. JAXA's Hayabusa2 and NASA's OSIRIS‐REx missions have returned samples from the C‐type asteroids Ryugu and Bennu, respectively. The chemical and mineralogical compositions of these samples closely resemble those of CI chondrites,
Tetsuya Yokoyama, Guillaume Avice, Henner Busemann, Nicolas Dauphas, Daniel P. Glavin, Ashley J. King, Thorsten Kleine, Katharina Lodders, Frederic Moynier, Maria Schönbächler, Yoshinori Takano, Kun Wang, Hikaru Yabuta, Yuma Enokido, Ryota Fukai, Shogo Tachibana, Tomohiro Usui   +16 more
wiley   +1 more source