Results 81 to 90 of about 7,923 (203)

Asking the 5 W's for designing next‐generation bioprocessing

AIChE Journal, Volume 72, Issue 9, September 2026.
Abstract Biotechnology is expanding beyond traditional, centralized fermentation and toward next‐generation bioprocessing paradigms that emphasize flexible deployment outside the laboratory with application‐specific performance. However, many bioprocesses fail to translate beyond proof‐of‐concept into industrially viable systems because early design ...
Sangdo Yook, Karoline Maria Vieira Nogueira, Raj Sukumar, Jenna Miller, Hal S. Alper   +4 more
wiley   +1 more source

Bridging Theory and Practice: Digital Twin Simulation of a Heat Exchanger in Laboratories for Engineering Students

Computer Applications in Engineering Education, Volume 34, Issue 5, September 2026.
ABSTRACT Digital twins serve as virtual replicas of physical systems. They can be used as a tool for engineering education by revealing the underlying principles behind unit operations. The project aimed to integrate digital twins into university engineering lab courses, complementing traditional methods by bridging the gap between experimentation and ...
Carles Troyano Ferré, Ruben Cabello, Pau Folch‐Millán, Alexandra Elena Plesu Popescu, Jordi Bonet Ruiz, Roger Bringué Tomàs   +5 more
wiley   +1 more source

Bacterial Lysis Observation Over Time Assay (BLOTS) for High‐Throughput Isolation, Sequencing, and Characterization of Bacteriophages

Current Protocols, Volume 6, Issue 9, September 2026.
Abstract Phages remain severely under‐sampled, largely due to the limitations of current isolation methods, which are labor‐intensive, low‐throughput, and often restricted to a narrow set of bacterial hosts. To address this gap, we developed a robust and scalable field‐to‐genome workflow that leverages laboratory automation to screen environmental ...
Sean Jia Le Pang, Soon Keong Wee, Bobby Guo Wei Lee, Odelia Yap, Eric Peng Huat Yap   +4 more
wiley   +1 more source

Profiles of Anxiety in Children Undergoing Elective Surgery: Predictors and Perioperative Outcomes

Developmental Psychobiology, Volume 68, Issue 5, September 2026.
ABSTRACT Surgery is an anxiety‐provoking event, but there are individual differences in the magnitude of experienced anxiety. The objective of this study was to identify patterns of children's preoperative anxiety, its predictors, and perioperative outcomes. The sample included 171 children (Mage = 9.95 years) undergoing elective surgery.
Kristie L. Poole, Cheryl H. T. Chow, Norman Buckley, Desigen Reddy, Ryan J. Van Lieshout, Louis A. Schmidt   +5 more
wiley   +1 more source

De Novo Assembly and Comparative Analysis of the Complete Mitochondrial Genome of Mesenchytraeus (Annelida, Enchytraeidae)

Ecology and Evolution, Volume 16, Issue 9, September 2026.
This present the first mitochondrial genome dataset for 13 Mesenchytraeus species from the Changbai Mountain glacial refugium. Beyond characterizing standard genomic features, we perform comparative analyses of gene order, nucleotide composition, codon usage, and control region structure.
Juanjuan Chen, Horacio Naveira, Junqian Zhang, Naicheng Wu, Zhicai Xie   +4 more
wiley   +1 more source

Unveiling the Functional Role of KIF21B in Microglia Inflammatory Response

Glia, Volume 74, Issue 9, September 2026.
Microglia express KIF21B in both sexes. KIF21B binds to microglia cytoskeleton; inflammation alters such interaction promoting a phagocytic state in females. In male microglia KIF21B modulates migration. ABSTRACT Microglia are brain immune cells that maintain homeostasis and respond to injury, changing cell morphology to drive inflammation, migration ...
Danny Ganchala, Alvaro Bautista‐Abad, Daniel Pinto‐Benito, Julia Simon‐Areces, Daniela Grassi, Francesco Paolo Ulloa Severino, Maria‐Angeles Arevalo   +6 more
wiley   +1 more source

AI‐Enhanced System for Diabetic Foot Ulcer Localization and Classification Using Multi‐Scale Neural CNN Model

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Diabetic foot ulcers (DFUs), which heal slowly because of inadequate blood supply, are among the serious infections and chronic foot problems that can result from diabetes mellitus (DM). The primary consequence of DFU, which can result in amputation if left untreated.
Md. Nur‐A‐Alam, Md. Anwar Hussen Wadud, Mostofa Kamal Nasir, Khandaker Mohammad Mohi Uddin   +3 more
wiley   +1 more source

MUC1 as a Survival Effector of Radiotherapy‐Induced Epithelial Hybrid States in Basal‐Like Breast Cancer

International Journal of Cancer, Volume 159, Issue 5, Page 1296-1310, 1 September 2026.
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki, Husam Bamahmoud, Nadine S. Georges, Shaishavi Jansari, Annika Jung, Daniela Grimm, Evangelos Prokakis, Fabian Alexander Gayer, Maryam Deldar, Christian Dullin, Julia Gallwas, Florian Wegwitz, Frauke Alves   +12 more
wiley   +1 more source

Ragomics‐Meta: An open‐source, scalable, reproducible, and extensible multi‐omics analysis workflow

iMetaOmics, Volume 3, Issue 3, September 2026.
Ragomics‐Meta is an open‐source, scalable, and reproducible multi‐omics workflow for metabolism‐centered analysis (https://www.raganetwork.com/). It integrates scRNA/snRNA‐seq, spatial transcriptomics, scATAC‐seq, and metabolomics modules to support quality control, dimensionality reduction, clustering, differential expression and accessibility ...
Zeping Gui, Huidong Su, Yuhao Chen, Jixing Yuan, Yexiu Gao, Ze Yu, Jing Zhang, Qingyi Zhu, Min Gu, Mulong Du, Zijie Wang, Ming Chen   +11 more
wiley   +1 more source

Immune Checkpoint Inhibitors in Cancer Therapy: Clinical Landscape, Resistance Mechanisms, and Therapeutic Innovations

MedComm – Oncology, Volume 5, Issue 3, September 2026.
The up‐to‐date clinical progress of immune checkpoint inhibitor (ICI) therapy in solid tumors, specifically the combinational regimens between ICIs and other treatment strategies, the mechanisms underlying primary and acquired resistance, and mechanism‐matched strategies to improve clinical outcomes are synthesized in this review.
Qiongyu Zhang, Zhi Qin, Caijuan Guo
wiley   +1 more source