iPepGen: a modular, immunopeptidogenomic analysis pipeline for discovery, verification, and prioritization of cancer peptide neoantigen candidates. [PDF]
Mehta S +12 more
europepmc +1 more source
Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan +19 more
wiley +1 more source
Mini-Galaxy: Rethinking Complex Human Diseases Through the Lens of Systems Biology and Multilayered AI Network Perspectives. [PDF]
Correia C +7 more
europepmc +1 more source
Subterranean environments contribute to three‐quarters of classified ecosystem services
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola +30 more
wiley +1 more source
Metatranscriptomic Reanalysis of Alzheimer's Brains Identifies Low-Biomass Microbial Signals Including Enrichment of <i>Acinetobacter radioresistens</i>. [PDF]
Guix FX.
europepmc +1 more source
miR‐21‐5p protects embryonic growth and heart function during developmental hypoxia by dampening HIF responses and shifting gene networks toward improved cardiomyocyte survival and calcium handling. This work identifies miR‐21‐5p as a promising therapeutic target for preventing fetal growth restriction and cardiovascular impairment in high‐risk ...
Bernardo J. Krause +12 more
wiley +1 more source
Alcohol-related liver disease disrupts bile acid homeostasis and gut microbial bile acid metabolism. [PDF]
Keller MI +24 more
europepmc +1 more source
The complete mitochondrial genome of Leptoseris columna was assembled using PacBio long read sequencing. ABSTRACT Leptoseris columna, a mesophotic coral species belonging to the family Agariciidae, is distributed throughout the Indo‐Pacific region.
Nomita Rani Adhikary +2 more
wiley +1 more source
Validity of Galaxy Watch for Estimating Energy Expenditure During Intermittent Running: Cross-Sectional Study. [PDF]
Ferreira ARP +7 more
europepmc +1 more source
Pleistocene glaciations have shaped freshwater fish evolution and distribution patterns across North America. This study investigated the phylogeographical history of the Western Blacknose Dace (Rhinichthys obtusus) using mitochondrial genomic data, revealing three major clades that diverged 2–1.5 million years ago during Pleistocene glaciations when ...
Adelina Rodriguez +7 more
wiley +1 more source

