Results 171 to 180 of about 19,184 (264)

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

open access: yesiMetaOmics, Volume 3, Issue 2, June 2026.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng   +15 more
wiley   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

open access: yesiMetaOmics, Volume 3, Issue 2, June 2026.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang   +6 more
wiley   +1 more source

Generating Advancements in Longitudinal Analysis in X and Y Variations: Rationale, Methods, and Diagnostic Characteristics for the GALAXY Registry. [PDF]

open access: yesAm J Med Genet A
Carl A   +14 more
europepmc   +1 more source

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody   +4 more
wiley   +1 more source

Exploring the prognostic impact and biological functions of mutant-like TP53-related genes in acute myeloid leukemia. [PDF]

open access: yesHematol Transfus Cell Ther
Bertoline LMF   +4 more
europepmc   +1 more source

Scheffrahnitermes ubuntu (Isoptera: Apicotermitinae), Description of a New Termite Using a Collaborative Approach to Address the Wallacean Shortfall

open access: yesNew Zealand Journal of Zoology, Volume 53, Issue 2, June 2026.
The study of Neotropical Apicotermitinae remains challenging due to the large number of undescribed taxa (Linnean shortfall) as well as the scarcity of distributional data (Wallacean shortfall). Despite recent efforts to reduce the first one, the second remains an even more significant challenge.
Camila C. Mellado   +10 more
wiley   +1 more source

Galaxy single-cell & spatial omics community update: Navigating new frontiers in 2025. [PDF]

open access: yesCell Genom
Loach M   +15 more
europepmc   +1 more source

Terrestrial Analogs to Titan for Geophysical Research

open access: yesReviews of Geophysics, Volume 64, Issue 2, June 2026.
Abstract Saturn's moon Titan exhibits remarkable parallels to the Earth in many geophysical and geological processes not found elsewhere in the solar system at the present day. These include a nitrogen atmosphere with a condensible gas—methane—replacing the Earth's water, leading to an active meteorology with rainfall and surface manifestations ...
Conor A. Nixon   +21 more
wiley   +1 more source

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