Results 81 to 90 of about 29,735,201 (297)

Additional file 2: of Nuclear FAM289-Galectin-1 interaction controls FAM289-mediated tumor promotion in malignant glioma

, 2019
Figure S2. Knockdown or overexpression of Galectin-1 in U251 or U87-MG cells. A. Galectin-1 was knocked down in U251 cell lines by SiRNA1–3. Galectin-1 siRNA2 and siRNA3 significantly reduced Galectin-1expression. B.
Shi Ma (217876), Yan Ding (39795), Qiu Zhang (239441), Long Dai (7356110), Xing Guo (103312), Yu Huang (15093), Mu Wu (7356107), Hao Peng (231482), Dong Li (212687), Xu Ruan (7356116), Meng Shan (7356113), Jun Tang (32983), Jue Wang (58890)   +12 more
core   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

The Examination of Viral Characteristics of HIV-1 CRF07_BC and Its Potential Interaction with Extracellular Galectin-3

Pathogens, 2020
HIV-1 CRF07_BC is a B’ and C subtype recombinant emerging virus and many of its viral characteristics remain unclear. Galectin-3 (Gal3) is a β-galactose binding lectin that has been reported as a pattern recognition receptor (PRR) and is known to mediate
Chih-Yen Lin, Wen-Hung Wang, Szu-Wei Huang, Chun-Sheng Yeh, Ruei-Yu Yuan, Zih-Syuan Yang, Aspiro Nayim Urbina, Sung-Pin Tseng, Po-Liang Lu, Yen-Hsu Chen, Sheng-Fan Wang   +10 more
doaj   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Galectin-1 receptors in different cell types

Journal of Biomedical Science, 2005
Galectins are a family of animal lectins defined by two properties: shared amino acid sequences in their carbohydrate-recognizing domain, and beta-galactoside affinity. A wide variety of biological phenomena are related to galectins, i.e., development, differentiation, morphogenesis, tumor metastasis, apoptosis, RNA splicing, and immunoregulatory ...
Elola, María Teresa, Chiesa, María Elena, Alberti, Alejandra Fernandez, Mordoh, José, Fink, Nilda Esther   +4 more
openaire   +3 more sources

Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]

, 2012
C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Lech, Maciej, Günthner, Roman, Regina Gröbmayr, Römmele, Christoph, Heni Eka Susanti, Susanti, Heni Eka, Heni Susanti, Maciej Lech, Roman Günthner, Hans-Joachim Anders, Christoph Römmele, Gröbmayr, Regina, Anders, Hans-Joachim   +12 more
core   +1 more source

Persistent Interleukin‐18 Fuels Expansion of CD38+HLA‐DR+CD8+ T Cells in Still Disease and Macrophage Activation Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease (SD) is an autoinflammatory disorder characterized by remarkably high interleukin‐18 (IL‐18) levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further
Greta Rogani, Remco G. A. Erkens, Alejandra Bodelón, Tim R. Mocking, Marein T. M. Putmans, Freya M. C. H. Huijsmans, Lyanne J. P. M. Sijbers, Aafke M. De Ligt, Maurice J. H. Van Haaren, Rianne C. Scholman, Noël M. M. Dautzenberg, Joyce I. Meesters‐Ensing, Martina Rossano, Laura Porretti, Stefan Nierkens, Francesca S. Minoia, Sebastiaan J. Vastert, Jorg van Loosdregt   +17 more
wiley   +1 more source

Serum Galectin‐1, Galectin‐9, and YKL‐40 levels in bipolar disorder and their relationship with cognitive functions

Brain and Behavior
Purpose The number of studies conducted on the role of neuroinflammation in the etiopathogenesis of bipolar disorder has been increasing in recent years.
Elcicek Selahaddin, Demir Bahadir, Sahin Sengul, Taysi Seyithan, Ulusal Hasan, Elboga Gülcin, Altindag Abdurrahman   +6 more
doaj   +1 more source

Galectins: a potential pharmacological target

Бюллетень сибирской медицины
Aim. To consider the use of galectin-1 and galectin-3 inhibitors as potential pharmacological targets in antitumor and antifibrotic therapy.The lecture includes the analysis of experimental research and review articles presented in the PubMed database. A
V. A. Serebryakova, O. E. Vaizova, E. L. Golovina, V. V. Kochubey   +3 more
doaj   +1 more source

Reduced expression of galectin-1 and galectin-9 by leucocytes in asthma patients

, 2012
Supported in part by EU–Mexico FONCICYT-C002-2009-1 ALA/127249, SAF-2008–02635 and SAF-2011–25834 from the Spanish Ministry of Science and Innovation, INDISNET (Redes Moleculares y Celulares en Enfermedades Inflamatorias) S2011/BMD-2332, MEICA (Molecular
Fuente, Hortensia de la, Lamana Domínguez, Amalia, Sanchez-Cuellar, Silvia, Giron, Rosa, Vara, Alicia, Cruz Adalia, Aranzazu, Ancochea, Julio, Cibrian, Danay, Sanchez-Madrid, Francisco   +8 more
core   +1 more source